# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4288256 | COR-510024; Table 23, R8C2 | F | = | 14.34 | % | ALA4257189 | % | ||||
2. | ALA4288256 | COR-510024; Table 23, R8C2 | MRTlast | = | 5.97 | hr | ALA4257188 | hr | ||||
3. | ALA4288256 | COR-510024; Table 23, R8C2 | %AUCextra | = | 44.85 | % | ALA4257187 | % | ||||
4. | ALA4288256 | COR-510024; Table 23, R8C2 | AUC | = | 2177 | ng.hr/ml | ALA4257186 | ng.hr.mL-1 | ||||
5. | ALA4288256 | COR-510024; Table 23, R8C2 | AUClast | = | 1201 | ng.hr/ml | ALA4257185 | ng.hr.mL-1 | ||||
6. | ALA4288256 | COR-510024; Table 23, R8C2 | t1/2 | = | 3.1 | hr | ALA4257184 | hr | ||||
7. | ALA4288256 | COR-510024; Table 23, R8C2 | Tmax | = | 4 | hr | ALA4257183 | hr | ||||
8. | ALA4288256 | COR-510024; Table 23, R8C2 | Cmax | = | 127 | ng/ml | ALA4257182 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
9. | ALA4288256 | COR-510024; Table 23, R8C2 | IC50 | = | 1370 | nM | ALA4257181 | 5.86 | nM | Homo sapiens | ||
10. | ALA4288256 | COR-510024; Table 23, R8C2 | IC50 | = | 873 | nM | ALA4257180 | 6.06 | nM | Homo sapiens | ||
11. | ALA4288256 | COR-510024; Table 23, R8C2 | IC50 | = | 10000 | nM | ALA4257179 | 5.00 | nM | Homo sapiens | ||
12. | ALA4288256 | COR-510024; Table 23, R8C2 | IC50 | = | 520 | nM | ALA4257178 | 6.28 | nM | Homo sapiens | ||
13. | ALA4288256 | COR-510024; Table 23, R8C2 | IC50 | = | 17 | nM | ALA4257176 | 7.77 | nM | Homo sapiens | ||
14. | ALA4288256 | COR-510024; Table 23, R8C2 | IC50 | = | 4 | nM | ALA4257177 | 8.40 | nM | Homo sapiens |