# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4288347 | 2; K-604 | IC50 | = | 0.026 | uM | ALA4265765 | 7.58 | nM | Homo sapiens | ||
2. | ALA4288347 | 2; K-604 | solubility | = | 19 | mg/ml | ALA4265766 | ug.mL-1 | ||||
3. | ALA4288347 | 2; K-604 | Tmax | = | 0.7 | hr | ALA4265767 | hr | Rattus norvegicus | |||
4. | ALA4288347 | 2; K-604 | Cmax | = | 192 | ng/ml | ALA4265768 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
5. | ALA4288347 | 2; K-604 | t1/2 | = | 2.1 | hr | ALA4265769 | hr | Rattus norvegicus | |||
6. | ALA4288347 | 2; K-604 | AUC | = | 594 | ng.hr/ml | ALA4265770 | ng.hr.mL-1 | Rattus norvegicus | |||
7. | ALA4288347 | 2; K-604 | Activity | = | 71 | % | ALA4265771 | % | Cricetinae | |||
8. | ALA4288347 | 2; K-604 | Activity | = | 53 | % | ALA4265772 | % | Cricetinae | |||
9. | ALA4288347 | 2; K-604 | Activity | = | 50 | % | ALA4265774 | % | Cricetinae | |||
10. | ALA4288347 | 2; K-604 | Activity | = | 37 | % | ALA4265775 | % | Cricetinae | |||
11. | ALA4288347 | 2; K-604 | Activity | 0 | ALA4265777 | Active | Cricetinae | |||||
12. | ALA4288347 | 2; K-604 | Activity | 0 | ALA4265778 | Non-Toxic | Cricetinae | |||||
13. | ALA4288347 | 2; K-604 | Activity | 0 | ALA4265783 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
14. | ALA4288347 | 2; K-604 | Activity | 0 | ALA4265784 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
15. | ALA4288347 | 2; K-604 | Activity | 0 | ALA4265785 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
16. | ALA4288347 | 2; K-604 | Activity | 0 | ALA4265786 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
17. | ALA4288347 | 2; K-604 | Activity | 0 | ALA4265787 | Non-Toxic | Escherichia coli | |||||
18. | ALA4288347 | 2; K-604 | Fu | = | 2.7 | % | ALA4265789 | |||||
19. | ALA4288347 | 2; K-604 | Tmax | = | 2.3 | hr | ALA4265790 | hr | Canis lupus familiaris | |||
20. | ALA4288347 | 2; K-604 | Tmax | = | 1 | hr | ALA4265791 | hr | Canis lupus familiaris |