Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	IC50	=	8	nM	ALA4257190	8.10		nM	Homo sapiens
2.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	IC50	=	12	nM	ALA4257191	7.92		nM	Homo sapiens
3.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	IC50	=	208	nM	ALA4257192	6.68		nM	Homo sapiens
4.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	IC50	=	350	nM	ALA4257193	6.46		nM	Homo sapiens
5.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	IC50	=	109	nM	ALA4257194	6.96		nM	Homo sapiens
6.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	Cmax	=	1018	ng/ml	ALA4257195		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
7.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	Tmax	=	3	hr	ALA4257196			hr
8.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	t1/2	=	6	hr	ALA4257197			hr
9.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	AUClast	=	8231	ng.hr/ml	ALA4257198			ng.hr.mL-1
10.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	AUC	=	14891	ng.hr/ml	ALA4257199			ng.hr.mL-1
11.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	%AUCextra	=	43.93	%	ALA4257200			%
12.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	MRTlast	=	5.56	hr	ALA4257201			hr
13.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	F	=	18421	%	ALA4257202			%
14.	ALA4289930	Table 23, R1C1; R14C3; Ex 40	IC50	=	880	nM	ALA4257203	6.06		nM	Homo sapiens