Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4290041	24	Fu	=	3.6	%	ALA4264810
2.	ALA4290041	24	F	=	39.9	%	ALA4264809			%	Rattus norvegicus
3.	ALA4290041	24	Tmax	=	2.5	hr	ALA4264808			hr	Rattus norvegicus
4.	ALA4290041	24	AUC	=	786	ng.hr/ml	ALA4264807			ng.hr.mL-1	Rattus norvegicus
5.	ALA4290041	24	Cmax	=	85.3	ng/ml	ALA4264806		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM	Rattus norvegicus
6.	ALA4290041	24	Vdss	=	1.7	L/Kg	ALA4264805			L.kg-1	Rattus norvegicus
7.	ALA4290041	24	t1/2	=	2.5	hr	ALA4264804			hr	Rattus norvegicus
8.	ALA4290041	24	CL	=	8.45	ml/min.kg	ALA4264803			mL.min-1.kg-1	Rattus norvegicus
9.	ALA4290041	24	AUC	=	986	ng.hr/ml	ALA4264802			ng.hr.mL-1	Rattus norvegicus
10.	ALA4290041	24	EC50	>	30	uM	ALA4264801			nM	Homo sapiens
11.	ALA4290041	24	EC50	>	30	uM	ALA4264800			nM	Homo sapiens
12.	ALA4290041	24	IC50	>	10	uM	ALA4264799			nM	Homo sapiens
13.	ALA4290041	24	IC50	>	10	uM	ALA4264798			nM	Homo sapiens
14.	ALA4290041	24	solubility	=	16	uM	ALA4264797			nM
15.	ALA4290041	24	solubility	=	26	uM	ALA4264796			nM
16.	ALA4290041	24	Stability	=	77	%	ALA4264795			%
17.	ALA4290041	24	Stability	=	63	%	ALA4264794			%
18.	ALA4290041	24	IC50	<	0.03	uM	ALA4264791			nM	Homo sapiens
19.	ALA4290041	24	Efficacy	=	85	%	ALA4264790			%	Mus musculus
20.	ALA4290041	24	IC50	=	0.25	uM	ALA4264790	6.60		nM	Mus musculus