# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4291768 | 65 | Activity | = | 34 | % | ALA4265772 | % | Cricetinae | |||
2. | ALA4291768 | 65 | Ratio IC50 | = | 1.8 | ALA4265764 | ||||||
3. | ALA4291768 | 65 | IC50 | = | 0.1 | uM | ALA4265765 | 7.00 | nM | Homo sapiens | ||
4. | ALA4291768 | 65 | solubility | = | 33 | mg/ml | ALA4265766 | ug.mL-1 | ||||
5. | ALA4291768 | 65 | Tmax | = | 0.5 | hr | ALA4265767 | hr | Rattus norvegicus | |||
6. | ALA4291768 | 65 | Cmax | = | 1038 | ng/ml | ALA4265768 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Rattus norvegicus | ||
7. | ALA4291768 | 65 | t1/2 | = | 3.4 | hr | ALA4265769 | hr | Rattus norvegicus | |||
8. | ALA4291768 | 65 | AUC | = | 2825 | ng.hr/ml | ALA4265770 | ng.hr.mL-1 | Rattus norvegicus | |||
9. | ALA4291768 | 65 | Activity | = | 49 | % | ALA4265771 | % | Cricetinae | |||
10. | ALA4291768 | 65 | Activity | = | 49 | % | ALA4265774 | % | Cricetinae | |||
11. | ALA4291768 | 65 | Activity | = | 34 | % | ALA4265775 | % | Cricetinae | |||
12. | ALA4291768 | 65 | Activity | 0 | ALA4265779 | Active | Cricetinae | |||||
13. | ALA4291768 | 65 | Activity | 0 | ALA4265780 | Non-Toxic | Cricetinae | |||||
14. | ALA4291768 | 65 | Activity | 0 | ALA4265783 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
15. | ALA4291768 | 65 | Activity | 0 | ALA4265784 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
16. | ALA4291768 | 65 | Activity | 0 | ALA4265785 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
17. | ALA4291768 | 65 | Activity | 0 | ALA4265786 | Non-Toxic | Salmonella enterica subsp. enterica serovar Typhimurium | |||||
18. | ALA4291768 | 65 | Activity | 0 | ALA4265787 | Non-Toxic | Escherichia coli | |||||
19. | ALA4291768 | 65 | Stability | 0 | ALA4265788 | Unstable | % | |||||
20. | ALA4291768 | 65 | fIC50 | = | 3.24 | nM | ALA4265804 | nM |