# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4293051 | 5 | F | = | 48 | % | ALA4427072 | % | ||||
2. | ALA4293051 | 5 | CL | = | 7013 | ml/hr/kg | ALA4427071 | mL.min-1.kg-1 | ||||
3. | ALA4293051 | 5 | Vz | = | 8014 | ml/kg | ALA4427070 | L.kg-1 | ||||
4. | ALA4293051 | 5 | AUC | = | 680 | ng.hr/ml | ALA4427069 | ng.hr.mL-1 | ||||
5. | ALA4293051 | 5 | AUC | = | 143 | ng.hr/ml | ALA4427068 | ng.hr.mL-1 | ||||
6. | ALA4293051 | 5 | AUCt | = | 673 | ng.hr/ml | ALA4427067 | ng.hr.mL-1 | ||||
7. | ALA4293051 | 5 | AUCt | = | 140 | ng.hr/ml | ALA4427066 | ng.hr.mL-1 | ||||
8. | ALA4293051 | 5 | Cmax | = | 136 | ng/ml | ALA4427065 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
9. | ALA4293051 | 5 | Cmax | = | 258 | ng/ml | ALA4427064 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
10. | ALA4293051 | 5 | Tmax | = | 2 | hr | ALA4427063 | hr | ||||
11. | ALA4293051 | 5 | Tmax | = | 0.9 | hr | ALA4427062 | hr | ||||
12. | ALA4293051 | 5 | t1/2 | = | 1.1 | hr | ALA4427061 | hr | ||||
13. | ALA4293051 | 5 | t1/2 | = | 0.8 | hr | ALA4427060 | hr | ||||
14. | ALA4293051 | 5 | INH | 0 | ALA4427057 | Active | % | Mus musculus | ||||
15. | ALA4293051 | 5 | INH | 0 | ALA4427056 | Active | % | Homo sapiens | ||||
16. | ALA4293051 | 5 | Activity | 0 | ALA4427055 | Non-Toxic | ||||||
17. | ALA4293051 | 5 | Activity | 0 | ALA4427054 | Non-Toxic | ||||||
18. | ALA4293051 | 5 | TGI | = | 50 | % | ALA4427052 | % | Homo sapiens | |||
19. | ALA4293051 | 5 | TGI | = | 52 | % | ALA4427051 | % | Homo sapiens | |||
20. | ALA4293051 | 5 | t1/2 | = | 51 | min | ALA4427050 | hr |