| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4293287 | 7 | Time | = | 24 | hr | ALA4269649 | hr | Rattus norvegicus | |||
| 2. | ALA4293287 | 7 | IC50 | = | 13 | nM | ALA4269648 | 7.89 | nM | Rattus norvegicus | ||
| 3. | ALA4293287 | 7 | IC50 | = | 19 | nM | ALA4269647 | 7.72 | nM | Rattus norvegicus | ||
| 4. | ALA4293287 | 7 | INH | > | 90 | % | ALA4269646 | % | Homo sapiens | |||
| 5. | ALA4293287 | 7 | INH | > | 90 | % | ALA4269645 | % | Homo sapiens | |||
| 6. | ALA4293287 | 7 | INH | > | 90 | % | ALA4269644 | % | Homo sapiens | |||
| 7. | ALA4293287 | 7 | INH | > | 90 | % | ALA4269643 | % | Homo sapiens | |||
| 8. | ALA4293287 | 7 | INH | > | 90 | % | ALA4269642 | % | Homo sapiens | |||
| 9. | ALA4293287 | 7 | INH | = | 89 | % | ALA4269641 | % | Homo sapiens | |||
| 10. | ALA4293287 | 7 | INH | = | 81 | % | ALA4269640 | % | Homo sapiens | |||
| 11. | ALA4293287 | 7 | Fu | = | 16.3 | % | ALA4269639 | |||||
| 12. | ALA4293287 | 7 | F | = | 96 | % | ALA4269638 | % | Canis lupus familiaris | |||
| 13. | ALA4293287 | 7 | AUC | = | 1900 | ng.hr/ml | ALA4269637 | ng.hr.mL-1 | Canis lupus familiaris | |||
| 14. | ALA4293287 | 7 | Cmax | = | 330 | ng/ml | ALA4269636 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | Canis lupus familiaris | ||
| 15. | ALA4293287 | 7 | t1/2 | = | 2.5 | hr | ALA4269635 | hr | Canis lupus familiaris | |||
| 16. | ALA4293287 | 7 | Vdss | = | 3.5 | L/Kg | ALA4269634 | L.kg-1 | Canis lupus familiaris | |||
| 17. | ALA4293287 | 7 | CL | = | 20 | ml/min.kg | ALA4269633 | mL.min-1.kg-1 | Canis lupus familiaris | |||
| 18. | ALA4293287 | 7 | t1/2 | = | 3.1 | hr | ALA4269632 | hr | Rattus norvegicus | |||
| 19. | ALA4293287 | 7 | Vdss | = | 1.1 | L/Kg | ALA4269631 | L.kg-1 | Rattus norvegicus | |||
| 20. | ALA4293287 | 7 | CL | = | 12 | ml/min.kg | ALA4269630 | mL.min-1.kg-1 | Rattus norvegicus |
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