| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  Simurosertib | SIMUROSERTIB | Drug metabolism | 0 | ALA4325383 | Metabolite_Notdetected | ||||||
| 2. | Simurosertib | SIMUROSERTIB | Drug metabolism | 0 | ALA4325382 | Metabolite_Notdetected | ||||||
| 3. | Simurosertib | SIMUROSERTIB | Drug metabolism | 0 | ALA4325381 | Metabolite_Notdetected | ||||||
| 4. | Simurosertib | SIMUROSERTIB | Drug metabolism | 0 | ALA4325375 | Metabolite_Notdetected | ||||||
| 5. | Simurosertib | SIMUROSERTIB | EC50 | = | 81 | nM | ALA4325333 | 7.09 | nM | Homo sapiens | ||
| 6. | Simurosertib | SIMUROSERTIB | IC50 | = | 17 | nM | ALA4325332 | 7.77 | nM | Homo sapiens | ||
| 7. | Simurosertib | SIMUROSERTIB | IC50 | = | 0.54 | nM | ALA4325331 | 9.27 | nM | Homo sapiens | ||
| 8. | Simurosertib | SIMUROSERTIB | IC50 | = | 43 | nM | ALA4325330 | 7.37 | nM | Homo sapiens | ||
| 9. | Simurosertib | SIMUROSERTIB | Ratio IC50 | = | 1700 | ALA4325329 | ||||||
| 10. | Simurosertib | SIMUROSERTIB | Ratio IC50 | = | 24000 | ALA4325328 | ||||||
| 11. | Simurosertib | SIMUROSERTIB | IC50 | = | 430 | nM | ALA4325327 | 6.37 | nM | Homo sapiens | ||
| 12. | Simurosertib | SIMUROSERTIB | IC50 | = | 6300 | nM | ALA4325326 | 5.20 | nM | Homo sapiens | ||
| 13. | Simurosertib | SIMUROSERTIB | IC50 | = | 0.26 | nM | ALA4325325 | 9.59 | nM | Homo sapiens | ||
| 14. | Simurosertib | SIMUROSERTIB | Time | = | 26 | min | ALA4325378 | hr | Homo sapiens | |||
| 15. | Simurosertib | SIMUROSERTIB | Kdiss | = | 6.3 | 10'-4/s | ALA4325377 | 10'-4/s | Homo sapiens | |||
| 16. | Simurosertib | SIMUROSERTIB | Kd | = | 4.24 | 10'-10M | ALA4325376 | 9.37 | nM | Homo sapiens |
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