# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4434955 | 9l | Activity | < | 5 | % | ALA4421202 | % | ||||
2. | ALA4434955 | 9l | T/C | = | 0.48 | ALA4421195 | Homo sapiens | |||||
3. | ALA4434955 | 9l | F | = | 74 | % | ALA4421192 | % | ||||
4. | ALA4434955 | 9l | t1/2 | = | 1 | hr | ALA4421190 | hr | ||||
5. | ALA4434955 | 9l | Cmax | = | 9.4 | uM | ALA4421188 | nM | ||||
6. | ALA4434955 | 9l | AUC | = | 12 | uM.hr | ALA4421186 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
7. | ALA4434955 | 9l | IC50 | > | 100 | uM | ALA4421185 | nM | Sus scrofa | |||
8. | ALA4434955 | 9l | IC50 | > | 100 | uM | ALA4421184 | nM | Homo sapiens | |||
9. | ALA4434955 | 9l | IC50 | = | 31 | uM | ALA4421183 | 4.51 | nM | Homo sapiens | ||
10. | ALA4434955 | 9l | IC50 | = | 0.26 | uM | ALA4421182 | 6.58 | nM | Homo sapiens | ||
11. | ALA4434955 | 9l | IC50 | = | 2.3 | uM | ALA4421180 | 5.64 | nM | Homo sapiens | ||
12. | ALA4434955 | 9l | IC50 | < | 0.18 | uM | ALA4421179 | nM | ||||
13. | ALA4434955 | 9l | IC50 | = | 0.77 | uM | ALA4421178 | 6.11 | nM | |||
14. | ALA4434955 | 9l | IC50 | > | 100 | uM | ALA4421175 | nM | ||||
15. | ALA4434955 | 9l | Papp | = | 25 | 10'-6 cm/s | ALA4305238 | 10'-6 cm/s | ||||
16. | ALA4434955 | 9l | Papp | = | 18 | 10'-6 cm/s | ALA4305237 | 10'-6 cm/s | ||||
17. | ALA4434955 | 9l | IC50 | = | 68 | uM | ALA4305236 | 4.17 | nM | Homo sapiens | ||
18. | ALA4434955 | 9l | IC50 | > | 100 | uM | ALA4305234 | nM | Homo sapiens | |||
19. | ALA4434955 | 9l | IC50 | = | 33 | uM | ALA4305233 | 4.48 | nM | Homo sapiens | ||
20. | ALA4434955 | 9l | IC50 | >= | 100 | uM | ALA4305232 | nM | Homo sapiens |