| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  HA-1077 dihydrochloride | Fasudil dihydrochloride | IC50 | = | 1.65 | uM | ALA5223827 | 5.78 | nM | |||
| 2. | HA-1077 dihydrochloride | Fasudil dihydrochloride | IC50 | = | 12.3 | uM | ALA5223826 | 4.91 | nM | Homo sapiens | ||
| 3. | HA-1077 dihydrochloride | Fasudil dihydrochloride | IC50 | = | 4.58 | uM | ALA5223825 | 5.34 | nM | Homo sapiens | ||
| 4. | HA-1077 dihydrochloride | Fasudil dihydrochloride | IC50 | = | 0.158 | uM | ALA5223824 | 6.80 | nM | Homo sapiens | ||
| 5. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Ki | = | 0.33 | uM | ALA5223823 | 6.48 | nM | Homo sapiens | ||
| 6. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 3.84 | % | ALA4342157 | % | Rattus norvegicus | |||
| 7. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 341.12 | um2 | ALA4342156 | um2 | Rattus norvegicus | |||
| 8. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 3.97 | % | ALA4342155 | % | Rattus norvegicus | |||
| 9. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 354.35 | um2 | ALA4342154 | um2 | Rattus norvegicus | |||
| 10. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 0.2 | ALA4342147 | Rattus norvegicus | |||||
| 11. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | 0 | ALA4342146 | Non-Toxic | Rattus norvegicus | |||||
| 12. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | 0 | ALA4342144 | Non-Toxic | Rattus norvegicus | |||||
| 13. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 6.71 | % | ALA4342148 | % | Rattus norvegicus | |||
| 14. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Kel | = | 0.91 | /hr | ALA4342112 | /hr | ||||
| 15. | HA-1077 dihydrochloride | Fasudil dihydrochloride | t1/2 | = | 0.867 | hr | ALA4342113 | hr | ||||
| 16. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Tmax | = | 0.25 | hr | ALA4342114 | hr | ||||
| 17. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Cmax | = | 84.2 | ng/ml | ALA4342115 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 18. | HA-1077 dihydrochloride | Fasudil dihydrochloride | AUCt | = | 55.4 | hr.ng/ml | ALA4342116 | ng.hr.mL-1 | ||||
| 19. | HA-1077 dihydrochloride | Fasudil dihydrochloride | AUC | = | 59.8 | hr.ng/ml | ALA4342117 | ng.hr.mL-1 | ||||
| 20. | HA-1077 dihydrochloride | Fasudil dihydrochloride | AUMCt | = | 52.8 | hr.hr.ng/ml | ALA4342118 | hr.hr.ng/ml |
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