# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 3.84 | % | ALA4342157 | % | Rattus norvegicus | |||
2. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 341.12 | um2 | ALA4342156 | um2 | Rattus norvegicus | |||
3. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 3.97 | % | ALA4342155 | % | Rattus norvegicus | |||
4. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 354.35 | um2 | ALA4342154 | um2 | Rattus norvegicus | |||
5. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 0.2 | ALA4342147 | Rattus norvegicus | |||||
6. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | 0 | ALA4342146 | Non-Toxic | Rattus norvegicus | |||||
7. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | 0 | ALA4342144 | Non-Toxic | Rattus norvegicus | |||||
8. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Activity | = | 6.71 | % | ALA4342148 | % | Rattus norvegicus | |||
9. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Kel | = | 0.91 | /hr | ALA4342112 | /hr | ||||
10. | HA-1077 dihydrochloride | Fasudil dihydrochloride | t1/2 | = | 0.867 | hr | ALA4342113 | hr | ||||
11. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Tmax | = | 0.25 | hr | ALA4342114 | hr | ||||
12. | HA-1077 dihydrochloride | Fasudil dihydrochloride | Cmax | = | 84.2 | ng/ml | ALA4342115 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
13. | HA-1077 dihydrochloride | Fasudil dihydrochloride | AUCt | = | 55.4 | hr.ng/ml | ALA4342116 | ng.hr.mL-1 | ||||
14. | HA-1077 dihydrochloride | Fasudil dihydrochloride | AUC | = | 59.8 | hr.ng/ml | ALA4342117 | ng.hr.mL-1 | ||||
15. | HA-1077 dihydrochloride | Fasudil dihydrochloride | AUMCt | = | 52.8 | hr.hr.ng/ml | ALA4342118 | hr.hr.ng/ml | ||||
16. | HA-1077 dihydrochloride | Fasudil dihydrochloride | AUMC | = | 75.7 | hr.hr.ng/ml | ALA4342119 | hr.hr.ng/ml | ||||
17. | HA-1077 dihydrochloride | Fasudil dihydrochloride | MRT | = | 1.2 | hr | ALA4342120 | hr | ||||
18. | HA-1077 dihydrochloride | Fasudil dihydrochloride | INH | 0 | ALA4342133 | Active | % | Rattus norvegicus | ||||
19. | HA-1077 dihydrochloride | Fasudil dihydrochloride | INH | 0 | ALA4342134 | Active | % | Rattus norvegicus | ||||
20. | HA-1077 dihydrochloride | Fasudil dihydrochloride | INH | 0 | ALA4342135 | Active | % | Rattus norvegicus |