| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4435396 | 14c | IC50 | > | 30 | uM | ALA4310471 | nM | Rattus norvegicus | |||
| 2. | ALA4435396 | 14c | IC50 | > | 30 | uM | ALA4310470 | nM | Rattus norvegicus | |||
| 3. | ALA4435396 | 14c | IC50 | > | 30 | uM | ALA4310469 | nM | Homo sapiens | |||
| 4. | ALA4435396 | 14c | IC50 | > | 30 | uM | ALA4310468 | nM | Rattus norvegicus | |||
| 5. | ALA4435396 | 14c | IC50 | > | 30 | uM | ALA4310467 | nM | Homo sapiens | |||
| 6. | ALA4435396 | 14c | IC50 | > | 30 | uM | ALA4310466 | nM | Homo sapiens | |||
| 7. | ALA4435396 | 14c | IC50 | > | 30 | uM | ALA4310465 | nM | Rattus norvegicus | |||
| 8. | ALA4435396 | 14c | Vdss | = | 6.59 | L/Kg | ALA4310464 | L.kg-1 | ||||
| 9. | ALA4435396 | 14c | t1/2 | = | 5.53 | hr | ALA4310463 | hr | ||||
| 10. | ALA4435396 | 14c | CL | = | 16.4 | ml/min.kg | ALA4310462 | mL.min-1.kg-1 | ||||
| 11. | ALA4435396 | 14c | Vdss | = | 3.31 | L/Kg | ALA4310461 | L.kg-1 | ||||
| 12. | ALA4435396 | 14c | t1/2 | = | 4.28 | hr | ALA4310460 | hr | ||||
| 13. | ALA4435396 | 14c | CL | = | 10 | ml/min.kg | ALA4310459 | mL.min-1.kg-1 | ||||
| 14. | ALA4435396 | 14c | K(p,uu,brain) | = | 0.86 | ALA4310458 | ||||||
| 15. | ALA4435396 | 14c | Kp | = | 4.04 | ALA4310457 | ||||||
| 16. | ALA4435396 | 14c | Fu | = | 0.007 | ALA4310456 | ||||||
| 17. | ALA4435396 | 14c | Fu | = | 0.01 | ALA4310455 | ||||||
| 18. | ALA4435396 | 14c | Fu | = | 0.03 | ALA4310454 | ||||||
| 19. | ALA4435396 | 14c | Emax | = | 2.4 | % | ALA4310453 | % | Rattus norvegicus | |||
| 20. | ALA4435396 | 14c | pIC50 | = | 6.1 | ALA4310452 | 6.10 | nM | Rattus norvegicus |
The page will load shortly, Thanks for your patience!