| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4435675 | 13a | Activity | 0 | ALA4349079 | Active | Rattus norvegicus | |||||
| 2. | ALA4435675 | 13a | Vz | = | 6.38 | L/Kg | ALA4349078 | L.kg-1 | ||||
| 3. | ALA4435675 | 13a | CL(app) | = | 2.54 | L/hr/kg | ALA4349077 | mL.min-1.kg-1 | ||||
| 4. | ALA4435675 | 13a | AUC | = | 198.19 | hr.ng/ml | ALA4349076 | ng.hr.mL-1 | ||||
| 5. | ALA4435675 | 13a | Cmax | = | 72.41 | ng/ml | ALA4349075 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 6. | ALA4435675 | 13a | Tmax | = | 1.25 | hr | ALA4349074 | hr | ||||
| 7. | ALA4435675 | 13a | t1/2 | = | 1.75 | hr | ALA4349073 | hr | ||||
| 8. | ALA4435675 | 13a | Vz | = | 41.14 | L/Kg | ALA4349072 | L.kg-1 | ||||
| 9. | ALA4435675 | 13a | CL(app) | = | 6.18 | L/hr/kg | ALA4349071 | mL.min-1.kg-1 | ||||
| 10. | ALA4435675 | 13a | AUC | = | 874.15 | hr.ng/ml | ALA4349070 | ng.hr.mL-1 | ||||
| 11. | ALA4435675 | 13a | Cmax | = | 175.11 | ng/ml | ALA4349069 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 12. | ALA4435675 | 13a | Tmax | = | 1.55 | hr | ALA4349068 | hr | ||||
| 13. | ALA4435675 | 13a | t1/2 | = | 3.77 | hr | ALA4349067 | hr | ||||
| 14. | ALA4435675 | 13a | Vz | = | 43.47 | L/Kg | ALA4349066 | L.kg-1 | ||||
| 15. | ALA4435675 | 13a | CL(app) | = | 5.76 | L/hr/kg | ALA4349065 | mL.min-1.kg-1 | ||||
| 16. | ALA4435675 | 13a | AUC | = | 372.7 | hr.ng/ml | ALA4349064 | ng.hr.mL-1 | ||||
| 17. | ALA4435675 | 13a | Cmax | = | 105.73 | ng/ml | ALA4349063 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 18. | ALA4435675 | 13a | Tmax | = | 0.75 | hr | ALA4349062 | hr | ||||
| 19. | ALA4435675 | 13a | t1/2 | = | 3.24 | hr | ALA4349061 | hr | ||||
| 20. | ALA4435675 | 13a | F | = | 80 | % | ALA4349060 | % |
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