# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4436020 | 54b; CWHM-1008 | ED99 | = | 30 | mg/kg/day | ALA4392059 | mg/kg/day | Plasmodium chabaudi | |||
2. | ALA4436020 | 54b; CWHM-1008 | Time | = | 24 | hr | ALA4392060 | hr | ||||
3. | ALA4436020 | 54b; CWHM-1008 | ED90 | = | 20 | mg/kg/day | ALA4392059 | mg/kg/day | Plasmodium chabaudi | |||
4. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 110 | nM | ALA4392058 | nM | ||||
5. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 10 | nM | ALA4392057 | nM | ||||
6. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 0 | nM | ALA4392056 | nM | ||||
7. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 1630 | nM | ALA4392055 | nM | ||||
8. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 960 | nM | ALA4392054 | nM | ||||
9. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 140 | nM | ALA4392053 | nM | ||||
10. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 2150 | nM | ALA4392052 | nM | ||||
11. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 1160 | nM | ALA4392051 | nM | ||||
12. | ALA4436020 | 54b; CWHM-1008 | Cp | = | 640 | nM | ALA4392050 | nM | ||||
13. | ALA4436020 | 54b; CWHM-1008 | INH | = | 98.7 | % | ALA4392049 | % | Plasmodium chabaudi | |||
14. | ALA4436020 | 54b; CWHM-1008 | INH | = | 75.2 | % | ALA4392048 | % | Plasmodium chabaudi | |||
15. | ALA4436020 | 54b; CWHM-1008 | INH | = | 22.4 | % | ALA4392047 | % | Plasmodium chabaudi | |||
16. | ALA4436020 | 54b; CWHM-1008 | F | = | 32 | % | ALA4392046 | % | ||||
17. | ALA4436020 | 54b; CWHM-1008 | Vz | = | 1.3 | L/Kg | ALA4392044 | L.kg-1 | ||||
18. | ALA4436020 | 54b; CWHM-1008 | CL(app) | = | 3.3 | ml/min.kg | ALA4392042 | mL.min-1.kg-1 | ||||
19. | ALA4436020 | 54b; CWHM-1008 | t1/2 | = | 4.4 | hr | ALA4392040 | hr | ||||
20. | ALA4436020 | 54b; CWHM-1008 | CLH | 0 | ALA4392038 | Not Determined |