# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4437135 | 23 | CLH | = | 198 | uL/min.mg | ALA4325035 | mL.min-1.g-1 | ||||
2. | ALA4437135 | 23 | CLH | = | 7.3 | uL/min | ALA4325034 | uL/min | ||||
3. | ALA4437135 | 23 | solubility | 0 | ALA4325080 | Insoluble | ||||||
4. | ALA4437135 | 23 | solubility | = | 30 | mg/ml | ALA4325077 | ug.mL-1 | ||||
5. | ALA4437135 | 23 | CL | = | 28 | ml/min.Kg | ALA4325076 | mL.min-1.kg-1 | ||||
6. | ALA4437135 | 23 | CL free | = | 93 | ml/min.Kg | ALA4325075 | mL.min-1.kg-1 | ||||
7. | ALA4437135 | 23 | Ratio | = | 4 | ALA4325070 | ||||||
8. | ALA4437135 | 23 | Activity | 0 | ALA4325069 | Not Active | ||||||
9. | ALA4437135 | 23 | fAUC | = | 1774 | ng.hr/ml | ALA4325067 | ng.hr.mL-1 | ||||
10. | ALA4437135 | 23 | Drug metabolism | < | 100 | pmol/mg.hr | ALA4325062 | pmol/mg.hr | ||||
11. | ALA4437135 | 23 | Activity | 0 | ALA4325066 | Not Active | Homo sapiens | |||||
12. | ALA4437135 | 23 | IC50 | > | 50 | uM | ALA4325065 | nM | Homo sapiens | |||
13. | ALA4437135 | 23 | IC50 | > | 50 | uM | ALA4325064 | nM | Homo sapiens | |||
14. | ALA4437135 | 23 | IC50 | > | 50 | uM | ALA4325063 | nM | Homo sapiens | |||
15. | ALA4437135 | 23 | MIC90 | > | 16 | ug ml-1 | ALA4325061 | ug.mL-1 | Stenotrophomonas maltophilia | |||
16. | ALA4437135 | 23 | MIC90 | = | 2 | ug ml-1 | ALA4325060 | ug.mL-1 | Pseudomonas aeruginosa | |||
17. | ALA4437135 | 23 | MIC90 | > | 16 | ug ml-1 | ALA4325059 | ug.mL-1 | Moraxella catarrhalis | |||
18. | ALA4437135 | 23 | MIC90 | <= | 0.03 | ug ml-1 | ALA4325058 | ug.mL-1 | Haemophilus influenzae | |||
19. | ALA4437135 | 23 | MIC90 | = | 16 | ug ml-1 | ALA4325057 | ug.mL-1 | Burkholderia cepacia | |||
20. | ALA4437135 | 23 | MIC90 | > | 16 | ug ml-1 | ALA4325056 | ug.mL-1 | Acinetobacter baumannii |