Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4439190	GSK3491943	fIC50	=	0.3	nM	ALA4384751			nM	Rattus norvegicus
2.	ALA4439190	GSK3491943	INH	=	99	%	ALA4384776			%	Rattus norvegicus
3.	ALA4439190	GSK3491943	Cp	=	152	nM	ALA4384772			nM
4.	ALA4439190	GSK3491943	Cp	=	52	nM	ALA4384771			nM
5.	ALA4439190	GSK3491943	Cp	=	14	nM	ALA4384770			nM
6.	ALA4439190	GSK3491943	IC50	=	3.2	nM	ALA4384769	8.49		nM	Homo sapiens
7.	ALA4439190	GSK3491943	AUCt/dose	=	3	hr.Kg/L	ALA4384760			hr.Kg/L
8.	ALA4439190	GSK3491943	AUCt/dose	=	2.9	hr.Kg/L	ALA4384759			hr.Kg/L
9.	ALA4439190	GSK3491943	AUCt/dose	=	0.4	hr.Kg/L	ALA4384758			hr.Kg/L
10.	ALA4439190	GSK3491943	AUCt/dose	=	0.5	hr.Kg/L	ALA4384757			hr.Kg/L
11.	ALA4439190	GSK3491943	AUCt	=	90	microg.hr/mL	ALA4384756			ng.hr.mL-1
12.	ALA4439190	GSK3491943	AUCt	=	2.5	microg.hr/mL	ALA4384755			ng.hr.mL-1
13.	ALA4439190	GSK3491943	AUCt	=	40	microg.hr/mL	ALA4384754			ng.hr.mL-1
14.	ALA4439190	GSK3491943	AUCt	=	1.1	microg.hr/mL	ALA4384753			ng.hr.mL-1
15.	ALA4439190	GSK3491943	Fu	=	4.2	%	ALA4384752
16.	ALA4439190	GSK3491943	IC50	=	33	nM	ALA4384751	7.48		nM	Rattus norvegicus
17.	ALA4439190	GSK3491943	IC50	=	4	nM	ALA4384750	8.40		nM	Rattus norvegicus
18.	ALA4439190	GSK3491943	TDI		0		ALA4384731		Not Active		Homo sapiens
19.	ALA4439190	GSK3491943	IC50	>	10	uM	ALA4384747			nM	Homo sapiens
20.	ALA4439190	GSK3491943	IC50	>	10	uM	ALA4384746			nM	Homo sapiens