| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4439424 | 24 | IC50 | = | 0 | uM | ALA4383512 | 9.70 | nM | Homo sapiens | ||
| 2. | ALA4439424 | 24 | IC50 | = | 0 | uM | ALA4383511 | 9.70 | nM | Homo sapiens | ||
| 3. | ALA4439424 | 24 | IC50 | = | 0.017 | uM | ALA4383510 | 7.77 | nM | Homo sapiens | ||
| 4. | ALA4439424 | 24 | IC50 | = | 0.002 | uM | ALA4383509 | 8.70 | nM | Homo sapiens | ||
| 5. | ALA4439424 | 24 | TGI | 0 | ALA4383508 | Active | Mus musculus | |||||
| 6. | ALA4439424 | 24 | TGI | 0 | ALA4383507 | Active | Mus musculus | |||||
| 7. | ALA4439424 | 24 | TGI | = | 52 | % | ALA4383506 | % | Mus musculus | |||
| 8. | ALA4439424 | 24 | TGI | = | 29 | % | ALA4383505 | % | Mus musculus | |||
| 9. | ALA4439424 | 24 | TGI | 0 | ALA4383504 | Dose-dependent effect | Mus musculus | |||||
| 10. | ALA4439424 | 24 | Activity | 0 | ALA4383503 | Non-Toxic | ||||||
| 11. | ALA4439424 | 24 | Activity | 0 | ALA4383502 | Non-Toxic | ||||||
| 12. | ALA4439424 | 24 | F | = | 10.9 | % | ALA4383501 | % | ||||
| 13. | ALA4439424 | 24 | MRT(t) | = | 4.4 | hr | ALA4383500 | hr | ||||
| 14. | ALA4439424 | 24 | MRT(t) | = | 1.2 | hr | ALA4383499 | hr | ||||
| 15. | ALA4439424 | 24 | CLz/F | = | 38 | L/hr/kg | ALA4383498 | L/hr/kg | ||||
| 16. | ALA4439424 | 24 | CLz/F | = | 5.1 | L/hr/kg | ALA4383497 | L/hr/kg | ||||
| 17. | ALA4439424 | 24 | Vz | = | 139.1 | L/Kg | ALA4383496 | L.kg-1 | ||||
| 18. | ALA4439424 | 24 | Vz | = | 17.7 | L/Kg | ALA4383495 | L.kg-1 | ||||
| 19. | ALA4439424 | 24 | AUC | = | 265.7 | hr.ng/ml | ALA4383494 | ng.hr.mL-1 | ||||
| 20. | ALA4439424 | 24 | AUC | = | 201.7 | hr.ng/ml | ALA4383493 | ng.hr.mL-1 |
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