# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4439637 | 49 | Activity | 0 | ALA4352749 | Active | Plasmodium berghei | |||||
2. | ALA4439637 | 49 | Activity | 0 | ALA4352748 | Active | Plasmodium berghei | |||||
3. | ALA4439637 | 49 | Activity | 0 | ALA4352747 | Active | Plasmodium berghei | |||||
4. | ALA4439637 | 49 | Survival | > | 35 | day | ALA4352746 | day | Plasmodium berghei | |||
5. | ALA4439637 | 49 | Activity | 0 | ALA4352745 | Active | Plasmodium berghei | |||||
6. | ALA4439637 | 49 | CLH | = | 787 | uL/min | ALA4352742 | uL/min | ||||
7. | ALA4439637 | 49 | Drug metabolism | 0 | ALA4352741 | Metabolite_Detected | ||||||
8. | ALA4439637 | 49 | Drug metabolism | 0 | ALA4352740 | Metabolite_Detected | ||||||
9. | ALA4439637 | 49 | Drug metabolism | 0 | ALA4352739 | Metabolite_Detected | ||||||
10. | ALA4439637 | 49 | Drug metabolism | 0 | ALA4352737 | Metabolite_Detected | ||||||
11. | ALA4439637 | 49 | Activity | 0 | ALA4352735 | Non-Toxic | Homo sapiens | |||||
12. | ALA4439637 | 49 | Activity | 0 | ALA4352734 | Active | Plasmodium falciparum | |||||
13. | ALA4439637 | 49 | t1/2 | = | 273 | min | ALA4352733 | hr | ||||
14. | ALA4439637 | 49 | t1/2 | = | 373 | min | ALA4352732 | hr | ||||
15. | ALA4439637 | 49 | IC50 | = | 4 | nM | ALA4352731 | 8.40 | nM | Plasmodium falciparum | ||
16. | ALA4439637 | 49 | IC50 | = | 1 | nM | ALA4352730 | 9.00 | nM | Plasmodium falciparum | ||
17. | ALA4439637 | 49 | IC50 | = | 112 | nM | ALA4352729 | 6.95 | nM | Plasmodium falciparum | ||
18. | ALA4439637 | 49 | IC50 | = | 33 | nM | ALA4352728 | 7.48 | nM | Plasmodium falciparum |