# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | T 3364366 | T-3364366 | Activity | 0 | ALA4433194 | Not Active | Rattus norvegicus | |||||
2. | T 3364366 | T-3364366 | Activity | 0 | ALA4433192 | Active | Homo sapiens | |||||
3. | T 3364366 | T-3364366 | Activity | 0 | ALA4433191 | Active | ||||||
4. | T 3364366 | T-3364366 | F | = | 41 | % | ALA4433190 | % | ||||
5. | T 3364366 | T-3364366 | MRT | = | 1.8 | hr | ALA4433189 | hr | ||||
6. | T 3364366 | T-3364366 | MRT | = | 0.65 | hr | ALA4433188 | hr | ||||
7. | T 3364366 | T-3364366 | Vdss | = | 1.1 | L/Kg | ALA4433187 | L.kg-1 | ||||
8. | T 3364366 | T-3364366 | CL | = | 1.5 | L/hr/kg | ALA4433186 | mL.min-1.kg-1 | ||||
9. | T 3364366 | T-3364366 | AUC | = | 260 | ng.hr/ml | ALA4433185 | ng.hr.mL-1 | ||||
10. | T 3364366 | T-3364366 | AUC | = | 65 | ng.hr/ml | ALA4433184 | ng.hr.mL-1 | ||||
11. | T 3364366 | T-3364366 | INH | 0 | ALA4433183 | Active | % | Homo sapiens | ||||
12. | T 3364366 | T-3364366 | Activity | 0 | ALA4433181 | Active | Rattus norvegicus | |||||
13. | T 3364366 | T-3364366 | t1/2 | = | 2 | hr | ALA4433180 | hr | Rattus norvegicus | |||
14. | T 3364366 | T-3364366 | Activity | < | 10 | % | ALA4433179 | % | Rattus norvegicus | |||
15. | T 3364366 | T-3364366 | Activity | 0 | ALA4433177 | Tde | Rattus norvegicus | |||||
16. | T 3364366 | T-3364366 | Kd(app) | = | 2.7 | nM | ALA4433176 | 8.57 | nM | Rattus norvegicus | ||
17. | T 3364366 | T-3364366 | IC50 | = | 2.1 | nM | ALA4433175 | 8.68 | nM | Rattus norvegicus | ||
18. | T 3364366 | T-3364366 | IC50 | = | 1.9 | nM | ALA4433174 | 8.72 | nM | Homo sapiens | ||
19. | T 3364366 | T-3364366 | IC50 | > | 10000 | nM | ALA4433173 | nM | Rattus norvegicus | |||
20. | T 3364366 | T-3364366 | IC50 | = | 6200 | nM | ALA4433172 | 5.21 | nM | Rattus norvegicus |