# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4440935 | 29; CYM-51317 | Ratio | = | 1 | ALA4424266 | ||||||
2. | ALA4440935 | 29; CYM-51317 | Papp | = | 26.2 | 10'-6 cm/s | ALA4424267 | 10'-6 cm/s | ||||
3. | ALA4440935 | 29; CYM-51317 | INH | < | 25 | % | ALA4424289 | % | Homo sapiens | |||
4. | ALA4440935 | 29; CYM-51317 | INH | < | 25 | % | ALA4424288 | % | Homo sapiens | |||
5. | ALA4440935 | 29; CYM-51317 | INH | < | 25 | % | ALA4424287 | % | Homo sapiens | |||
6. | ALA4440935 | 29; CYM-51317 | INH | = | 32 | % | ALA4424286 | % | Homo sapiens | |||
7. | ALA4440935 | 29; CYM-51317 | INH | = | 35 | % | ALA4424285 | % | Homo sapiens | |||
8. | ALA4440935 | 29; CYM-51317 | INH | = | 5 | % | ALA4424284 | % | Homo sapiens | |||
9. | ALA4440935 | 29; CYM-51317 | INH | = | -6 | % | ALA4424283 | % | Homo sapiens | |||
10. | ALA4440935 | 29; CYM-51317 | INH | = | 20 | % | ALA4424282 | % | Homo sapiens | |||
11. | ALA4440935 | 29; CYM-51317 | INH | = | 4 | % | ALA4424281 | % | Homo sapiens | |||
12. | ALA4440935 | 29; CYM-51317 | PPB | = | 78 | % | ALA4424280 | % | ||||
13. | ALA4440935 | 29; CYM-51317 | PPB | = | 64 | % | ALA4424279 | % | ||||
14. | ALA4440935 | 29; CYM-51317 | PPB | = | 71 | % | ALA4424278 | % | ||||
15. | ALA4440935 | 29; CYM-51317 | CLH | = | 14.1 | ml/min.kg | ALA4424277 | mL.min-1.kg-1 | ||||
16. | ALA4440935 | 29; CYM-51317 | CLH | = | 7.1 | ml/min.kg | ALA4424276 | mL.min-1.kg-1 | ||||
17. | ALA4440935 | 29; CYM-51317 | CLH | = | 15.1 | ml/min.kg | ALA4424275 | mL.min-1.kg-1 | ||||
18. | ALA4440935 | 29; CYM-51317 | Ratio IC50 | = | 26 | ALA4424271 | ||||||
19. | ALA4440935 | 29; CYM-51317 | IC50 | = | 4410 | nM | ALA4424270 | 5.36 | nM | Homo sapiens | ||
20. | ALA4440935 | 29; CYM-51317 | IC50 | = | 79 | nM | ALA4424269 | 7.10 | nM | Homo sapiens |