# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4441262 | 2j | IC50 | = | 7.3 | uM | ALA4835453 | 5.14 | nM | |||
2. | ALA4441262 | 2j | IC50 | = | 24 | nM | ALA4835452 | 7.62 | nM | Homo sapiens | ||
3. | ALA4441262 | 2j | Ratio IC50 | = | 59 | ALA4835451 | ||||||
4. | ALA4441262 | 2j | IC50 | = | 1.6 | nM | ALA4835450 | 8.80 | nM | Homo sapiens | ||
5. | ALA4441262 | 2j | CL | = | 370 | ml/min.kg | ALA4348898 | mL.min-1.kg-1 | ||||
6. | ALA4441262 | 2j | CL | = | 58 | ml/min.kg | ALA4348897 | mL.min-1.kg-1 | ||||
7. | ALA4441262 | 2j | IC50 | = | 94 | nM | ALA4348830 | 7.03 | nM | Homo sapiens | ||
8. | ALA4441262 | 2j | Ratio IC50 | = | 57 | ALA4348894 | ||||||
9. | ALA4441262 | 2j | logD | = | 0.8 | ALA4348883 | ||||||
10. | ALA4441262 | 2j | PPB | = | 51 | % | ALA4348853 | % | ||||
11. | ALA4441262 | 2j | t1/2 | = | 0.4 | hr | ALA4348851 | hr | ||||
12. | ALA4441262 | 2j | Vdu | = | 4 | L/Kg | ALA4348850 | L.kg-1 | ||||
13. | ALA4441262 | 2j | Vd | = | 1.8 | L/Kg | ALA4348849 | L.kg-1 | ||||
14. | ALA4441262 | 2j | IC50 | = | 1.6 | nM | ALA4348831 | 8.80 | nM | Homo sapiens | ||
15. | ALA4441262 | 2j | IC50 | > | 20000 | nM | ALA4348846 | nM | Homo sapiens | |||
16. | ALA4441262 | 2j | IC50 | > | 20000 | nM | ALA4348845 | nM | Homo sapiens | |||
17. | ALA4441262 | 2j | IC50 | > | 20000 | nM | ALA4348844 | nM | Homo sapiens | |||
18. | ALA4441262 | 2j | IC50 | > | 20000 | nM | ALA4348843 | nM | Homo sapiens | |||
19. | ALA4441262 | 2j | IC50 | > | 20000 | nM | ALA4348842 | nM | Homo sapiens | |||
20. | ALA4441262 | 2j | IC50 | > | 20000 | nM | ALA4348841 | nM | Homo sapiens |