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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4441346	16g	IC50	=	4.2	nM	ALA4383872	8.38		nM	Homo sapiens
2.	ALA4441346	16g	IC50	=	3.5	nM	ALA4383871	8.46		nM	Homo sapiens
3.	ALA4441346	16g	Activity		0		ALA4383893		Active		Rattus norvegicus
4.	ALA4441346	16g	Activity		0		ALA4383877		Dose-dependent effect		Rattus norvegicus
5.	ALA4441346	16g	Activity		0		ALA4383878		Dose-dependent effect		Rattus norvegicus
6.	ALA4441346	16g	Activity		0		ALA4383885		Toxic
7.	ALA4441346	16g	F	=	51.3	%	ALA4383892			%
8.	ALA4441346	16g	Vdss	=	0.201	L/Kg	ALA4383891			L.kg-1
9.	ALA4441346	16g	CL	=	0.92	L/hr/kg	ALA4383890			mL.min-1.kg-1
10.	ALA4441346	16g	AUC	=	2258	ng.hr/ml	ALA4383889			ng.hr.mL-1
11.	ALA4441346	16g	beta t1/2	=	8.8	hr	ALA4383870			hr
12.	ALA4441346	16g	AUC	=	1160	ng.hr/ml	ALA4383888			ng.hr.mL-1
13.	ALA4441346	16g	beta t1/2	=	9.6	hr	ALA4383887			hr
14.	ALA4441346	16g	Tmax	=	3.2	hr	ALA4383886			hr
15.	ALA4441346	16g	Cmax	=	221	ng/ml	ALA4383869		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
16.	ALA4441346	16g	Activity		0		ALA4383884		Dose-dependent effect
17.	ALA4441346	16g	Activity	=	67	%	ALA4383883			%	Rattus norvegicus
18.	ALA4441346	16g	Activity	=	50	%	ALA4383882			%	Rattus norvegicus
19.	ALA4441346	16g	Activity	=	30	%	ALA4383868			%	Rattus norvegicus
20.	ALA4441346	16g	Activity	=	54	%	ALA4383881			%	Rattus norvegicus