# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4442570 | 8g | AUC | = | 0.591 | microg.hr/mL | ALA4388750 | ng.hr.mL-1 | ||||
2. | ALA4442570 | 8g | Cmax | = | 0.096 | ug ml-1 | ALA4388749 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
3. | ALA4442570 | 8g | Activity | = | 47 | % | ALA4388737 | % | Homo sapiens | |||
4. | ALA4442570 | 8g | INH | = | 20 | % | ALA4388746 | % | Homo sapiens | |||
5. | ALA4442570 | 8g | INH | = | 10 | % | ALA4388745 | % | Homo sapiens | |||
6. | ALA4442570 | 8g | INH | = | 10 | % | ALA4388744 | % | Homo sapiens | |||
7. | ALA4442570 | 8g | INH | = | 17 | % | ALA4388743 | % | Homo sapiens | |||
8. | ALA4442570 | 8g | INH | = | 10 | % | ALA4388738 | % | Homo sapiens | |||
9. | ALA4442570 | 8g | Stability | = | 12 | % | ALA4388742 | % | ||||
10. | ALA4442570 | 8g | Stability | = | 60 | % | ALA4388741 | % | ||||
11. | ALA4442570 | 8g | solubility | = | 0.3 | ug ml-1 | ALA4388740 | ug.mL-1 | ||||
12. | ALA4442570 | 8g | EC200 | = | 0.001 | ug ml-1 | ALA4388739 | ug ml-1 | Mus musculus | |||
13. | ALA4442570 | 8g | IC50 | = | 4.5 | nM | ALA5030091 | 8.35 | nM | Homo sapiens | ||
14. | ALA4442570 | 8g | EC200 | = | 0.5 | ng/ml | ALA5030080 | ng/ml |