# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4443587 | 43 | BPR | = | 1.33 | ALA4355773 | ||||||
2. | ALA4443587 | 43 | Drug uptake | = | 0.133 | nmol/g | ALA4355771 | nmol/g | ||||
3. | ALA4443587 | 43 | FC | = | 2 | ALA4355769 | Rattus norvegicus | |||||
4. | ALA4443587 | 43 | F | = | 93.8 | % | ALA4355768 | % | ||||
5. | ALA4443587 | 43 | Vdss | = | 1.72 | L/Kg | ALA4355765 | L.kg-1 | ||||
6. | ALA4443587 | 43 | t1/2 | = | 1.48 | hr | ALA4355762 | hr | ||||
7. | ALA4443587 | 43 | CL | = | 27.1 | ml/min.kg | ALA4355760 | mL.min-1.kg-1 | ||||
8. | ALA4443587 | 43 | AUC/dose | = | 2.54 | uM.hr.kg/mg | ALA4355759 | uM.hr.kg/mg | ||||
9. | ALA4443587 | 43 | Fu | = | 83 | % | ALA4355757 | |||||
10. | ALA4443587 | 43 | EC50 | = | 1.71 | nM | ALA4355755 | 8.77 | nM | Rattus norvegicus | ||
11. | ALA4443587 | 43 | Ki | = | 0.36 | nM | ALA4355754 | 9.44 | nM | Homo sapiens | ||
12. | ALA4443587 | 43 | Fu | = | 77 | % | ALA4355753 | |||||
13. | ALA4443587 | 43 | Papp | = | 5.7 | 10'-6 cm/s | ALA4355751 | 10'-6 cm/s | ||||
14. | ALA4443587 | 43 | Ki | = | 1300 | nM | ALA4355756 | 5.89 | nM | Homo sapiens |