# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4443619 | 2 | Ratio Ki | > | 1000 | ALA4426691 | ||||||
2. | ALA4443619 | 2 | Ratio Ki | > | 1000 | ALA4426692 | ||||||
3. | ALA4443619 | 2 | Ratio Ki | > | 1000 | ALA4426693 | ||||||
4. | ALA4443619 | 2 | Ratio Ki | > | 1000 | ALA4426694 | ||||||
5. | ALA4443619 | 2 | solubility | > | 100 | uM | ALA4426695 | nM | ||||
6. | ALA4443619 | 2 | logD | = | -0.5 | ALA4426696 | ||||||
7. | ALA4443619 | 2 | Papp | = | 0.1 | ucm/s | ALA4426697 | ucm/s | ||||
8. | ALA4443619 | 2 | Ratio | = | 2.4 | ALA4426698 | ||||||
9. | ALA4443619 | 2 | Drug metabolism | 0 | ALA4426701 | Metabolite_Detected | ||||||
10. | ALA4443619 | 2 | Drug metabolism | 0 | ALA4426702 | Metabolite_Detected | ||||||
11. | ALA4443619 | 2 | Cmax | = | 0.004 | umol/L | ALA4426722 | nM | ||||
12. | ALA4443619 | 2 | F | = | 0.5 | % | ALA4426721 | % | ||||
13. | ALA4443619 | 2 | AUC | = | 0.003 | hr.umol/L | ALA4426720 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
14. | ALA4443619 | 2 | betat1/2(app) | = | 0.56 | hr | ALA4426719 | hr | ||||
15. | ALA4443619 | 2 | AUC | = | 0.258 | hr.umol/L | ALA4426718 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
16. | ALA4443619 | 2 | betat1/2(app) | = | 0.35 | hr | ALA4426717 | hr | ||||
17. | ALA4443619 | 2 | Vdss | = | 0.23 | L/Kg | ALA4426716 | L.kg-1 | ||||
18. | ALA4443619 | 2 | CL | = | 32.4 | ml/min.kg | ALA4426715 | mL.min-1.kg-1 | ||||
19. | ALA4443619 | 2 | Drug metabolism | 0 | ALA4426714 | Metabolite_Detected | ||||||
20. | ALA4443619 | 2 | Drug metabolism | 0 | ALA4426713 | Metabolite_Detected |