| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4443828 | 19h | IC50 | = | 27 | nM | ALA5232564 | 7.57 | nM | Homo sapiens | ||
| 2. | ALA4443828 | 19h | Selectivity ratio | = | 2 | ALA4371515 | ||||||
| 3. | ALA4443828 | 19h | Activity | 0 | ALA4371513 | Non-Toxic | ||||||
| 4. | ALA4443828 | 19h | Ratio IC50 | > | 50 | ALA4371512 | ||||||
| 5. | ALA4443828 | 19h | Activity | = | 14.3 | % | ALA4371509 | % | Homo sapiens | |||
| 6. | ALA4443828 | 19h | Activity | = | 65.7 | % | ALA4371508 | % | Homo sapiens | |||
| 7. | ALA4443828 | 19h | TGI | 0 | ALA4371506 | Active | Homo sapiens | |||||
| 8. | ALA4443828 | 19h | Activity | 0 | ALA4371504 | Toxic | ||||||
| 9. | ALA4443828 | 19h | Vz | = | 10.2 | L/Kg | ALA4371499 | L.kg-1 | ||||
| 10. | ALA4443828 | 19h | t1/2 lambda z | = | 18.7 | hr | ALA4371498 | hr | ||||
| 11. | ALA4443828 | 19h | C0 | = | 310 | ng/ml | ALA4371497 | ng/ml | Mus musculus | |||
| 12. | ALA4443828 | 19h | CL | = | 0.4 | L/hr/kg | ALA4371496 | mL.min-1.kg-1 | ||||
| 13. | ALA4443828 | 19h | AUCt | = | 1433 | ng.hr/ml | ALA4371495 | ng.hr.mL-1 | ||||
| 14. | ALA4443828 | 19h | AUC | = | 2646 | ng.hr/ml | ALA4371494 | ng.hr.mL-1 | ||||
| 15. | ALA4443828 | 19h | PPB | = | 97.2 | % | ALA4371493 | % | ||||
| 16. | ALA4443828 | 19h | PPB | = | 99.1 | % | ALA4371492 | % | ||||
| 17. | ALA4443828 | 19h | Stability | = | 108 | % | ALA4371491 | % | ||||
| 18. | ALA4443828 | 19h | Stability | = | 96.3 | % | ALA4371490 | % | ||||
| 19. | ALA4443828 | 19h | CLH | = | 143.3 | microL/min/mg | ALA4371489 | mL.min-1.g-1 | ||||
| 20. | ALA4443828 | 19h | CLH | = | 60.5 | microL/min/mg | ALA4371488 | mL.min-1.g-1 |
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