| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4444446 | 22 | FC | = | 18.44 | ALA4355777 | Rattus norvegicus | |||||
| 2. | ALA4444446 | 22 | AUC | = | 1.963 | nM.hr/g | ALA4355776 | nM.hr/g | ||||
| 3. | ALA4444446 | 22 | Tmax | = | 8 | hr | ALA4355775 | hr | ||||
| 4. | ALA4444446 | 22 | BPR | >= | 29.5 | ALA4355774 | ||||||
| 5. | ALA4444446 | 22 | BPR | = | 1.67 | ALA4355773 | ||||||
| 6. | ALA4444446 | 22 | Drug uptake | = | 0.074 | nmol/g | ALA4355772 | nmol/g | ||||
| 7. | ALA4444446 | 22 | Drug uptake | = | 0.099 | nmol/g | ALA4355771 | nmol/g | ||||
| 8. | ALA4444446 | 22 | FC | = | 1.45 | ALA4355770 | Rattus norvegicus | |||||
| 9. | ALA4444446 | 22 | FC | = | 2.13 | ALA4355769 | Rattus norvegicus | |||||
| 10. | ALA4444446 | 22 | F | = | 70.4 | % | ALA4355768 | % | ||||
| 11. | ALA4444446 | 22 | Vdss | = | 2 | L/Kg | ALA4355766 | L.kg-1 | ||||
| 12. | ALA4444446 | 22 | t1/2 | = | 1.27 | hr | ALA4355763 | hr | ||||
| 13. | ALA4444446 | 22 | CL | = | 36.8 | ml/min.kg | ALA4355761 | mL.min-1.kg-1 | ||||
| 14. | ALA4444446 | 22 | AUC/dose | = | 1.43 | uM.hr.kg/mg | ALA4355759 | uM.hr.kg/mg | ||||
| 15. | ALA4444446 | 22 | Fu | = | 96 | % | ALA4355757 | |||||
| 16. | ALA4444446 | 22 | EC50 | = | 10.6 | nM | ALA4355755 | 7.97 | nM | Rattus norvegicus | ||
| 17. | ALA4444446 | 22 | Ki | = | 0.53 | nM | ALA4355754 | 9.28 | nM | Homo sapiens | ||
| 18. | ALA4444446 | 22 | Fu | = | 84 | % | ALA4355753 | |||||
| 19. | ALA4444446 | 22 | Ki | > | 10000 | nM | ALA4355756 | nM | Homo sapiens |
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