# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4444494 | WHZ-13 | EC50 | > | 11.1 | uM | ALA4364851 | nM | Homo sapiens | |||
2. | ALA4444494 | WHZ-13 | INH | 0 | ALA4364843 | Dose-dependent effect | % | Homo sapiens | ||||
3. | ALA4444494 | WHZ-13 | INH | 0 | ALA4364842 | Dose-dependent effect | % | Homo sapiens | ||||
4. | ALA4444494 | WHZ-13 | INH | 0 | ALA4364841 | Dose-dependent effect | % | |||||
5. | ALA4444494 | WHZ-13 | CLH | = | 97 | microL/min/mg | ALA4364862 | mL.min-1.g-1 | ||||
6. | ALA4444494 | WHZ-13 | CLH | = | 61 | microL/min/mg | ALA4364861 | mL.min-1.g-1 | ||||
7. | ALA4444494 | WHZ-13 | CLH | = | 61 | microL/min/mg | ALA4364860 | mL.min-1.g-1 | ||||
8. | ALA4444494 | WHZ-13 | permeability | = | 203 | nm/s | ALA4364859 | nm/s | ||||
9. | ALA4444494 | WHZ-13 | Ratio EC50 | = | 152 | ALA4364858 | Plasmodium falciparum | |||||
10. | ALA4444494 | WHZ-13 | Ratio EC50 | = | 19 | ALA4364857 | Plasmodium falciparum | |||||
11. | ALA4444494 | WHZ-13 | EC50 | = | 501.5 | nM | ALA4364856 | 6.30 | nM | Plasmodium falciparum | ||
12. | ALA4444494 | WHZ-13 | EC50 | = | 61.9 | nM | ALA4364855 | 7.21 | nM | Plasmodium falciparum | ||
13. | ALA4444494 | WHZ-13 | EC50 | = | 3.3 | nM | ALA4364854 | 8.48 | nM | Plasmodium falciparum | ||
14. | ALA4444494 | WHZ-13 | EC50 | = | 7.1 | nM | ALA4364853 | 8.15 | nM | Plasmodium falciparum | ||
15. | ALA4444494 | WHZ-13 | EC50 | > | 11000 | nM | ALA4364850 | nM | Homo sapiens | |||
16. | ALA4444494 | WHZ-13 | INH | 0 | ALA4364847 | Dose-dependent effect | % | |||||
17. | ALA4444494 | WHZ-13 | Ratio IC50 | = | 24 | ALA4364846 | ||||||
18. | ALA4444494 | WHZ-13 | Ratio IC50 | = | 91 | ALA4364845 | ||||||
19. | ALA4444494 | WHZ-13 | EC50 | = | 3.1 | nM | ALA4364844 | 8.51 | nM | Plasmodium falciparum | ||
20. | ALA4444494 | WHZ-13 | IC50 | = | 112 | nM | ALA4364843 | 6.95 | nM | Homo sapiens |