| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4445645 | 1; CCT369260 | CL | = | 20 | ml | ALA5223615 | ml | ||||
| 2. | ALA4445645 | 1; CCT369260 | DC50 | = | 0.09 | uM | ALA5223614 | uM | Homo sapiens | |||
| 3. | ALA4445645 | 1; CCT369260 | IC50 | = | 0.52 | uM | ALA5223601 | 6.28 | nM | Homo sapiens | ||
| 4. | ALA4445645 | 1; CCT369260 | PPB | = | 99.96 | % | ALA5168587 | % | ||||
| 5. | ALA4445645 | 1; CCT369260 | F | = | 54 | % | ALA5168586 | % | ||||
| 6. | ALA4445645 | 1; CCT369260 | Vdss | = | 2.1 | L/Kg | ALA5168585 | L.kg-1 | ||||
| 7. | ALA4445645 | 1; CCT369260 | t1/2 | = | 1.4 | hr | ALA5168584 | hr | ||||
| 8. | ALA4445645 | 1; CCT369260 | CL free | = | 46731 | ml/min.kg | ALA5168583 | mL.min-1.kg-1 | ||||
| 9. | ALA4445645 | 1; CCT369260 | CLH | = | 22 | % | ALA5168582 | % | ||||
| 10. | ALA4445645 | 1; CCT369260 | CL | = | 19.8 | ml/min.kg | ALA5168581 | mL.min-1.kg-1 | ||||
| 11. | ALA4445645 | 1; CCT369260 | Cmax | = | 1577 | nM/L | ALA5168580 | nM | ||||
| 12. | ALA4445645 | 1; CCT369260 | permeability | = | 33 | 10^-6 cm/s | ALA5168572 | 10^-6 cm/s | ||||
| 13. | ALA4445645 | 1; CCT369260 | CLH | = | 10 | uL/min | ALA5168571 | uL/min | ||||
| 14. | ALA4445645 | 1; CCT369260 | CLH | = | 11 | uL/min | ALA5168570 | uL/min | ||||
| 15. | ALA4445645 | 1; CCT369260 | Fu | = | 0.022 | % | ALA5168569 | |||||
| 16. | ALA4445645 | 1; CCT369260 | Kinetic_solubility | = | 11 | uM | ALA5168567 | nM | ||||
| 17. | ALA4445645 | 1; CCT369260 | logD | = | 4.3 | ALA5168566 | ||||||
| 18. | ALA4445645 | 1; CCT369260 | CLH | = | 78 | uL/min | ALA5168565 | uL/min | ||||
| 19. | ALA4445645 | 1; CCT369260 | Emax | = | 96 | % | ALA5168564 | % | Homo sapiens | |||
| 20. | ALA4445645 | 1; CCT369260 | EC50 | = | 54 | nM | ALA5168563 | 7.27 | nM | Homo sapiens |
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