| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4446835 | 10 | Activity | = | 35 | % | ALA5251039 | % | ||||
| 2. | ALA4446835 | 10 | solubility | = | 1 | ug ml-1 | ALA5251036 | ug.mL-1 | ||||
| 3. | ALA4446835 | 10 | IC50 | < | 0.3 | nM | ALA5251035 | nM | Homo sapiens | |||
| 4. | ALA4446835 | 10 | F | = | 0.29 | % | ALA5251028 | % | ||||
| 5. | ALA4446835 | 10 | solubility | = | 1 | ug ml-1 | ALA5251027 | ug.mL-1 | ||||
| 6. | ALA4446835 | 10 | IC50 | = | 150 | nM | ALA5251026 | 6.82 | nM | Homo sapiens | ||
| 7. | ALA4446835 | 10 | IC50 | = | 4.8 | nM | ALA5251025 | 8.32 | nM | Homo sapiens | ||
| 8. | ALA4446835 | 10 | IC50 | > | 40 | uM | ALA4313152 | nM | Homo sapiens | |||
| 9. | ALA4446835 | 10 | F | = | 0.29 | % | ALA4313125 | % | ||||
| 10. | ALA4446835 | 10 | t1/2 | = | 1.77 | hr | ALA4313124 | hr | ||||
| 11. | ALA4446835 | 10 | MRT | = | 2.17 | hr | ALA4313123 | hr | ||||
| 12. | ALA4446835 | 10 | AUC | = | 6.4 | ng.hr/ml | ALA4313122 | ng.hr.mL-1 | ||||
| 13. | ALA4446835 | 10 | AUCt | = | 6.4 | ng.hr/ml | ALA4313121 | ng.hr.mL-1 | ||||
| 14. | ALA4446835 | 10 | Cmax | = | 12.9 | ng/ml | ALA4313120 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 15. | ALA4446835 | 10 | Tmax | = | 0.861 | hr | ALA4313119 | hr | ||||
| 16. | ALA4446835 | 10 | CL | = | 8.6 | L/hr/kg | ALA4313117 | mL.min-1.kg-1 | ||||
| 17. | ALA4446835 | 10 | t1/2 | = | 6.25 | hr | ALA4313116 | hr | ||||
| 18. | ALA4446835 | 10 | MRT | = | 5.04 | hr | ALA4313115 | hr | ||||
| 19. | ALA4446835 | 10 | AUC | = | 1272.4 | ng.hr/ml | ALA4313114 | ng.hr.mL-1 | ||||
| 20. | ALA4446835 | 10 | AUCt | = | 1093.9 | ng.hr/ml | ALA4313113 | ng.hr.mL-1 |
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