| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4447685 | 2a; Z25180415 | Ratio IC50 | = | 4 | ALA4400020 | ||||||
| 2. | ALA4447685 | 2a; Z25180415 | Kinetic_solubility | = | 35.4 | uM | ALA4400015 | nM | ||||
| 3. | ALA4447685 | 2a; Z25180415 | Papp | = | 0.5 | 10'-6 cm/s | ALA4400014 | 10'-6 cm/s | ||||
| 4. | ALA4447685 | 2a; Z25180415 | Papp | = | 0.4 | 10'-6 cm/s | ALA4400013 | 10'-6 cm/s | ||||
| 5. | ALA4447685 | 2a; Z25180415 | t1/2 | = | 3 | min | ALA4400012 | hr | ||||
| 6. | ALA4447685 | 2a; Z25180415 | t1/2 | = | 11.5 | min | ALA4400011 | hr | ||||
| 7. | ALA4447685 | 2a; Z25180415 | IC50 | = | 428.6 | nM | ALA4400010 | 6.37 | nM | Rattus norvegicus | ||
| 8. | ALA4447685 | 2a; Z25180415 | IC50 | = | 112.6 | nM | ALA4400009 | 6.95 | nM | Homo sapiens | ||
| 9. | ALA4447685 | 2a; Z25180415 | IC50 | = | 47.1 | nM | ALA4400008 | 7.33 | nM | Homo sapiens | ||
| 10. | ALA4447685 | 2a; Z25180415 | IC50 | = | 60.5 | nM | ALA4400007 | 7.22 | nM | Homo sapiens | ||
| 11. | ALA4447685 | 2a; Z25180415 | IC50 | = | 12.1 | nM | ALA4400006 | 7.92 | nM | Homo sapiens | ||
| 12. | ALA4447685 | 2a; Z25180415 | IC50 | = | 20000 | nM | ALA4399999 | 4.70 | nM | Homo sapiens | ||
| 13. | ALA4447685 | 2a; Z25180415 | IC50 | = | 86.5 | nM | ALA4399998 | 7.06 | nM | Homo sapiens | ||
| 14. | ALA4447685 | 2a; Z25180415 | IC50 | = | 3 | nM | ALA4399997 | 8.52 | nM | Homo sapiens | ||
| 15. | ALA4447685 | 2a; Z25180415 | INH | = | 101.9 | % | ALA4399996 | % | Homo sapiens | |||
| 16. | ALA4447685 | 2a; Z25180415 | INH | = | 99 | % | ALA4399995 | % | Homo sapiens |
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