Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	ALA4448433	10a	Activity	=	59	%	ALA4386482		%	Homo sapiens
2.	ALA4448433	10a	TGI		0		ALA4386483	Active		Homo sapiens
3.	ALA4448433	10a	INH	=	95.9	%	ALA4386480		%	Mus musculus
4.	ALA4448433	10a	INH	=	85	%	ALA4386481		%	Mus musculus
5.	ALA4448433	10a	Activity		0		ALA4386550	Dose-dependent effect		Mus musculus
6.	ALA4448433	10a	F	=	38	%	ALA4386549		%
7.	ALA4448433	10a	AUC	=	2796	ng/mL.hr	ALA4386545		ng.hr.mL-1
8.	ALA4448433	10a	Cmax	=	562	ng/ml	ALA4386544	standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
9.	ALA4448433	10a	t1/2	=	2.8	hr	ALA4386548		hr
10.	ALA4448433	10a	CL	=	20.2	ml/min.kg	ALA4386547		mL.min-1.kg-1
11.	ALA4448433	10a	Vdss	=	7.1	L/Kg	ALA4386546		L.kg-1
12.	ALA4448433	10a	INH		0		ALA4386541	Active	%	Homo sapiens
13.	ALA4448433	10a	INH		0		ALA4386540	Active	%	Homo sapiens
14.	ALA4448433	10a	INH		0		ALA4386539	Active	%	Homo sapiens
15.	ALA4448433	10a	INH		0		ALA4386538	Active	%	Homo sapiens
16.	ALA4448433	10a	GI50	=	14.6	uM	ALA4386537		nM	Homo sapiens
17.	ALA4448433	10a	GI50	>	20	uM	ALA4386536		nM	Homo sapiens
18.	ALA4448433	10a	GI50	>	10	uM	ALA4386535		nM	Homo sapiens
19.	ALA4448433	10a	GI50	>	100	nM	ALA4386534		nM
20.	ALA4448433	10a	GI50	>	100	nM	ALA4386533		nM