| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4448591 | 1 | INH | 0 | ALA4404882 | Not Active | % | Homo sapiens | ||||
| 2. | ALA4448591 | 1 | Activity | 0 | ALA4404881 | Not Active | Homo sapiens | |||||
| 3. | ALA4448591 | 1 | Activity | 0 | ALA4404880 | Not Active | Homo sapiens | |||||
| 4. | ALA4448591 | 1 | Activity | 0 | ALA4404879 | Not Active | Homo sapiens | |||||
| 5. | ALA4448591 | 1 | Activity | 0 | ALA4404878 | Not Active | Homo sapiens | |||||
| 6. | ALA4448591 | 1 | pEC50 | = | 5.42 | ALA4404877 | 5.42 | nM | Mus musculus | |||
| 7. | ALA4448591 | 1 | pEC50 | = | 5.87 | ALA4404876 | 5.87 | nM | Rattus norvegicus | |||
| 8. | ALA4448591 | 1 | F | = | 73 | % | ALA4404875 | % | ||||
| 9. | ALA4448591 | 1 | AUC | = | 865000 | ng.min/ml | ALA4404874 | ng.hr.mL-1 | ||||
| 10. | ALA4448591 | 1 | Cmax | = | 7470 | ng/ml | ALA4404873 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA4448591 | 1 | Tmax | = | 15 | min | ALA4404872 | hr | ||||
| 12. | ALA4448591 | 1 | t1/2 | = | 89.7 | min | ALA4404871 | hr | ||||
| 13. | ALA4448591 | 1 | CL | = | 8.45 | ml/min.kg | ALA4404870 | mL.min-1.kg-1 | ||||
| 14. | ALA4448591 | 1 | Vd | = | 759 | ml/kg | ALA4404869 | L.kg-1 | ||||
| 15. | ALA4448591 | 1 | t1/2 | = | 62.2 | min | ALA4404868 | hr | ||||
| 16. | ALA4448591 | 1 | Stability | = | 52 | % | ALA4404867 | % | ||||
| 17. | ALA4448591 | 1 | pEC50 | = | 6.27 | ALA4404864 | 6.27 | nM | Homo sapiens | |||
| 18. | ALA4448591 | 1 | Emax | = | 105 | % | ALA4404863 | % | Homo sapiens | |||
| 19. | ALA4448591 | 1 | pEC50 | = | 6.28 | ALA4404862 | 6.28 | nM | Homo sapiens | |||
| 20. | ALA4448591 | 1 | Emax | = | 100 | % | ALA4404861 | % | Homo sapiens |
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