| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4448724 | 11 | IC50 | > | 10 | uM | ALA4417040 | nM | Homo sapiens | |||
| 2. | ALA4448724 | 11 | Activity | 0 | ALA4417078 | Non-Toxic | ||||||
| 3. | ALA4448724 | 11 | Activity | 0 | ALA4417070 | Non-Toxic | ||||||
| 4. | ALA4448724 | 11 | T/C | = | 45 | % | ALA4417069 | % | Homo sapiens | |||
| 5. | ALA4448724 | 11 | Ratio | = | 17 | ALA4417068 | ||||||
| 6. | ALA4448724 | 11 | Papp | = | 3.34 | 10'-6 cm/s | ALA4417067 | 10'-6 cm/s | ||||
| 7. | ALA4448724 | 11 | Drug recovery | = | 2.3 | % | ALA4417036 | % | ||||
| 8. | ALA4448724 | 11 | t1/2 | = | 1.1 | hr | ALA4417057 | hr | ||||
| 9. | ALA4448724 | 11 | Vdss | = | 0.44 | L/Kg | ALA4417056 | L.kg-1 | ||||
| 10. | ALA4448724 | 11 | CL | = | 0.28 | L/hr/kg | ALA4417055 | mL.min-1.kg-1 | ||||
| 11. | ALA4448724 | 11 | Ratio | = | 0.13 | ALA4417054 | ||||||
| 12. | ALA4448724 | 11 | AUC | = | 44 | ng/mL.hr | ALA4417053 | ng.hr.mL-1 | ||||
| 13. | ALA4448724 | 11 | Fu | = | 3.5 | % | ALA4417052 | |||||
| 14. | ALA4448724 | 11 | Fu | = | 3.4 | % | ALA4417051 | |||||
| 15. | ALA4448724 | 11 | Ratio | = | 1.5 | ALA4417050 | ||||||
| 16. | ALA4448724 | 11 | permeability | = | 24 | 10'-6 cm/s | ALA4417049 | 10'-6 cm/s | ||||
| 17. | ALA4448724 | 11 | solubility | = | 122 | ug ml-1 | ALA4417048 | ug.mL-1 | ||||
| 18. | ALA4448724 | 11 | Activity | >= | 50 | % | ALA4417044 | % | Homo sapiens | |||
| 19. | ALA4448724 | 11 | Time | = | 15.9 | min | ALA4417043 | hr | Homo sapiens | |||
| 20. | ALA4448724 | 11 | Kd | = | 1.14 | nM | ALA4417042 | 8.94 | nM | Homo sapiens |
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