# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4448829 | 42; SGE-301 | F | = | 28 | % | ALA5136788 | % | ||||
2. | ALA4448829 | 42; SGE-301 | t1/2 | = | 1.7 | hr | ALA5136787 | hr | ||||
3. | ALA4448829 | 42; SGE-301 | CL | = | 1.1 | L/hr/kg | ALA5136786 | mL.min-1.kg-1 | ||||
4. | ALA4448829 | 42; SGE-301 | Ratio | = | 0.6 | ALA5136744 | ||||||
5. | ALA4448829 | 42; SGE-301 | F | = | 17 | % | ALA5136743 | % | ||||
6. | ALA4448829 | 42; SGE-301 | F | = | 23 | % | ALA5136742 | % | ||||
7. | ALA4448829 | 42; SGE-301 | F | = | 53 | % | ALA5136741 | % | ||||
8. | ALA4448829 | 42; SGE-301 | CL | = | 0.2 | L/hr/kg | ALA5136740 | mL.min-1.kg-1 | ||||
9. | ALA4448829 | 42; SGE-301 | CL | = | 1.8 | L/hr/kg | ALA5136739 | mL.min-1.kg-1 | ||||
10. | ALA4448829 | 42; SGE-301 | CL | = | 1.1 | L/hr/kg | ALA5136738 | mL.min-1.kg-1 | ||||
11. | ALA4448829 | 42; SGE-301 | CLH | = | 13 | microL/min/mg | ALA5136737 | mL.min-1.g-1 | ||||
12. | ALA4448829 | 42; SGE-301 | CLH | = | 16 | microL/min/mg | ALA5136736 | mL.min-1.g-1 | ||||
13. | ALA4448829 | 42; SGE-301 | CLH | = | 3.3 | L/hr/kg | ALA5136729 | mL.min-1.kg-1 | ||||
14. | ALA4448829 | 42; SGE-301 | CLH | = | 2 | L/hr/kg | ALA5136728 | mL.min-1.kg-1 | ||||
15. | ALA4448829 | 42; SGE-301 | CLH | = | 0.4 | L/hr/kg | ALA5136727 | mL.min-1.kg-1 | ||||
16. | ALA4448829 | 42; SGE-301 | CLH | = | 42 | microL/min/mg | ALA5136726 | mL.min-1.g-1 | ||||
17. | ALA4448829 | 42; SGE-301 | solubility | = | 0.62 | uM | ALA5136725 | nM | ||||
18. | ALA4448829 | 42; SGE-301 | logD | = | 5 | ALA5136724 | ||||||
19. | ALA4448829 | 42; SGE-301 | Emax | = | 92 | % | ALA5136723 | % | Homo sapiens | |||
20. | ALA4448829 | 42; SGE-301 | EC50 | = | 38 | nM | ALA5136722 | 7.42 | nM | Homo sapiens |