# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4449532 | (S,R)-4c | INH | 0 | ALA4331654 | Active | % | Plasmodium falciparum (isolate 3D7) | ||||
2. | ALA4449532 | (S,R)-4c | INH | 0 | ALA4331653 | Active | % | Plasmodium falciparum (isolate 3D7) | ||||
3. | ALA4449532 | (S,R)-4c | IC50 | = | 1.1 | uM | ALA4331652 | 5.96 | nM | Plasmodium falciparum | ||
4. | ALA4449532 | (S,R)-4c | IC50 | = | 1.1 | uM | ALA4331651 | 5.96 | nM | Plasmodium falciparum | ||
5. | ALA4449532 | (S,R)-4c | Ratio IC50 | = | 20 | ALA4331650 | ||||||
6. | ALA4449532 | (S,R)-4c | EC50 | = | 1.5 | nM | ALA4331649 | 8.82 | nM | Plasmodium falciparum | ||
7. | ALA4449532 | (S,R)-4c | IC50 | = | 1 | uM | ALA4331648 | 6.00 | nM | Homo sapiens | ||
8. | ALA4449532 | (S,R)-4c | IC50 | = | 0.05 | uM | ALA4331647 | 7.30 | nM | Plasmodium falciparum |