| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4450159 | 10 | IC50 | > | 10 | uM | ALA4417040 | nM | Homo sapiens | |||
| 2. | ALA4450159 | 10 | Drug recovery | < | 1 | % | ALA4417036 | % | ||||
| 3. | ALA4450159 | 10 | t1/2 | = | 0.82 | hr | ALA4417057 | hr | ||||
| 4. | ALA4450159 | 10 | Vdss | = | 0.99 | L/Kg | ALA4417056 | L.kg-1 | ||||
| 5. | ALA4450159 | 10 | CL | = | 1.15 | L/hr/kg | ALA4417055 | mL.min-1.kg-1 | ||||
| 6. | ALA4450159 | 10 | Ratio | = | 0.02 | ALA4417054 | ||||||
| 7. | ALA4450159 | 10 | AUC | = | 38 | ng/mL.hr | ALA4417053 | ng.hr.mL-1 | ||||
| 8. | ALA4450159 | 10 | Fu | = | 19 | % | ALA4417052 | |||||
| 9. | ALA4450159 | 10 | Fu | = | 19 | % | ALA4417051 | |||||
| 10. | ALA4450159 | 10 | Ratio | = | 3.7 | ALA4417050 | ||||||
| 11. | ALA4450159 | 10 | permeability | = | 14 | 10'-6 cm/s | ALA4417049 | 10'-6 cm/s | ||||
| 12. | ALA4450159 | 10 | solubility | = | 157 | ug ml-1 | ALA4417048 | ug.mL-1 | ||||
| 13. | ALA4450159 | 10 | IC50 | = | 72 | nM | ALA4417039 | 7.14 | nM | Homo sapiens | ||
| 14. | ALA4450159 | 10 | IC50 | = | 80 | nM | ALA4417038 | 7.10 | nM | Homo sapiens |
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