# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4450474 | 12h | INH | 0 | ALA4398020 | Dose-dependent effect | % | Homo sapiens | ||||
2. | ALA4450474 | 12h | Activity | 0 | ALA4398019 | Dose-dependent effect | Homo sapiens | |||||
3. | ALA4450474 | 12h | Activity | 0 | ALA4397988 | Dose-dependent effect | Homo sapiens | |||||
4. | ALA4450474 | 12h | Activity | 0 | ALA4398018 | Non-Toxic | ||||||
5. | ALA4450474 | 12h | Activity | 0 | ALA4398017 | Active | Homo sapiens | |||||
6. | ALA4450474 | 12h | TGI | = | 62.7 | % | ALA4398016 | % | Homo sapiens | |||
7. | ALA4450474 | 12h | Vdss | = | 3.46 | L/Kg | ALA4398015 | L.kg-1 | ||||
8. | ALA4450474 | 12h | CL | = | 76.3 | ml/kg/min | ALA4398014 | mL.min-1.kg-1 | ||||
9. | ALA4450474 | 12h | AUC | = | 874 | ng/mL.hr | ALA4398013 | ng.hr.mL-1 | ||||
10. | ALA4450474 | 12h | AUCt | = | 868 | ng/mL.hr | ALA4398012 | ng.hr.mL-1 | ||||
11. | ALA4450474 | 12h | t1/2 | = | 2.59 | hr | ALA4398011 | hr | ||||
12. | ALA4450474 | 12h | INH | 0 | ALA4398010 | Active | % | Homo sapiens | ||||
13. | ALA4450474 | 12h | Activity | 0 | ALA4398009 | Active | Homo sapiens | |||||
14. | ALA4450474 | 12h | Activity | 0 | ALA4398008 | Active | Homo sapiens | |||||
15. | ALA4450474 | 12h | Activity | = | 66.48 | % | ALA4398007 | % | Homo sapiens | |||
16. | ALA4450474 | 12h | Activity | = | 9.52 | % | ALA4398006 | % | Homo sapiens | |||
17. | ALA4450474 | 12h | Activity | = | 24 | % | ALA4398005 | % | Homo sapiens | |||
18. | ALA4450474 | 12h | Activity | = | 59.87 | % | ALA4398004 | % | Homo sapiens | |||
19. | ALA4450474 | 12h | Activity | = | 9.74 | % | ALA4398003 | % | Homo sapiens | |||
20. | ALA4450474 | 12h | Activity | = | 30.39 | % | ALA4398002 | % | Homo sapiens |