| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4451402 | 12 | IC50 | > | 10 | uM | ALA4417040 | nM | Homo sapiens | |||
| 2. | ALA4451402 | 12 | Activity | 0 | ALA4417079 | Non-Toxic | ||||||
| 3. | ALA4451402 | 12 | Activity | 0 | ALA4417072 | Non-Toxic | ||||||
| 4. | ALA4451402 | 12 | T/C | = | 39 | % | ALA4417071 | % | Homo sapiens | |||
| 5. | ALA4451402 | 12 | Ratio | = | 41 | ALA4417068 | ||||||
| 6. | ALA4451402 | 12 | Papp | = | 1.28 | 10'-6 cm/s | ALA4417067 | 10'-6 cm/s | ||||
| 7. | ALA4451402 | 12 | Drug recovery | < | 1 | % | ALA4417036 | % | ||||
| 8. | ALA4451402 | 12 | t1/2 | = | 1.5 | hr | ALA4417057 | hr | ||||
| 9. | ALA4451402 | 12 | Vdss | = | 0.51 | L/Kg | ALA4417056 | L.kg-1 | ||||
| 10. | ALA4451402 | 12 | CL | = | 0.32 | L/hr/kg | ALA4417055 | mL.min-1.kg-1 | ||||
| 11. | ALA4451402 | 12 | Ratio | = | 0.18 | ALA4417054 | ||||||
| 12. | ALA4451402 | 12 | AUC | = | 220 | ng/mL.hr | ALA4417053 | ng.hr.mL-1 | ||||
| 13. | ALA4451402 | 12 | Fu | = | 7.5 | % | ALA4417052 | |||||
| 14. | ALA4451402 | 12 | Fu | = | 22 | % | ALA4417051 | |||||
| 15. | ALA4451402 | 12 | Ratio | = | 3.9 | ALA4417050 | ||||||
| 16. | ALA4451402 | 12 | permeability | = | 19 | 10'-6 cm/s | ALA4417049 | 10'-6 cm/s | ||||
| 17. | ALA4451402 | 12 | solubility | = | 94 | ug ml-1 | ALA4417048 | ug.mL-1 | ||||
| 18. | ALA4451402 | 12 | Activity | 0 | ALA4417045 | Active | Homo sapiens | |||||
| 19. | ALA4451402 | 12 | Activity | >= | 50 | % | ALA4417044 | % | Homo sapiens | |||
| 20. | ALA4451402 | 12 | Time | = | 9.8 | min | ALA4417043 | hr | Homo sapiens |
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