# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4451854 | 1o | Activity | 0 | ALA4307049 | Dose-dependent effect | Homo sapiens | |||||
2. | ALA4451854 | 1o | INH | 0 | ALA4307048 | Active | % | Homo sapiens | ||||
3. | ALA4451854 | 1o | TGI | = | 42.07 | % | ALA4307047 | % | Homo sapiens | |||
4. | ALA4451854 | 1o | TGI | = | 40.7 | % | ALA4307046 | % | Homo sapiens | |||
5. | ALA4451854 | 1o | Activity | 0 | ALA4307045 | Toxic | ||||||
6. | ALA4451854 | 1o | Stability | > | 99 | % | ALA4307044 | % | ||||
7. | ALA4451854 | 1o | Stability | > | 99 | % | ALA4307043 | % | ||||
8. | ALA4451854 | 1o | Stability | = | 88.3 | % | ALA4307042 | % | ||||
9. | ALA4451854 | 1o | Stability | = | 81.3 | % | ALA4307041 | % | ||||
10. | ALA4451854 | 1o | Stability | = | 63.7 | % | ALA4307040 | % | ||||
11. | ALA4451854 | 1o | Stability | = | 82.7 | % | ALA4307039 | % | ||||
12. | ALA4451854 | 1o | INH | = | 40 | % | ALA4307038 | % | Homo sapiens | |||
13. | ALA4451854 | 1o | AUC | = | 1507.7 | ug/L.hr | ALA4307037 | ng.hr.mL-1 | ||||
14. | ALA4451854 | 1o | AUCt | = | 1481.1 | ug/L.hr | ALA4307036 | ng.hr.mL-1 | ||||
15. | ALA4451854 | 1o | Cmax | = | 1439 | ug/L | ALA4307035 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
16. | ALA4451854 | 1o | t1/2 | = | 3.52 | hr | ALA4307034 | hr | ||||
17. | ALA4451854 | 1o | Tmax | = | 0.083 | hr | ALA4307033 | hr | ||||
18. | ALA4451854 | 1o | F | = | 52 | % | ALA4307032 | % | ||||
19. | ALA4451854 | 1o | AUC | = | 3940.5 | ug/L.hr | ALA4307031 | ng.hr.mL-1 | ||||
20. | ALA4451854 | 1o | AUCt | = | 3886 | ug/L.hr | ALA4307030 | ng.hr.mL-1 |