# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4452474 | 5b | pEC50 | = | 7.6 | ALA4326358 | 7.60 | nM | Homo sapiens | |||
2. | ALA4452474 | 5b | pEC50 | = | 7 | ALA4326358 | 7.00 | nM | Homo sapiens | |||
3. | ALA4452474 | 5b | Activity | = | 9.55 | ml/kg | ALA4326394 | ml/kg | Rattus norvegicus | |||
4. | ALA4452474 | 5b | Activity | = | 10.6 | ml/kg | ALA4326393 | ml/kg | Rattus norvegicus | |||
5. | ALA4452474 | 5b | Activity | = | 9.55 | ml/kg | ALA4326392 | ml/kg | Rattus norvegicus | |||
6. | ALA4452474 | 5b | Activity | 0 | ALA4326391 | Dose-dependent effect | Rattus norvegicus | |||||
7. | ALA4452474 | 5b | Drug uptake | = | 527 | nM | ALA4326390 | nM | ||||
8. | ALA4452474 | 5b | Tmax | = | 60 | min | ALA4326389 | hr | ||||
9. | ALA4452474 | 5b | Tmax | = | 15 | min | ALA4326388 | hr | ||||
10. | ALA4452474 | 5b | Activity | = | 17.9 | /min | ALA4326387 | /min | Rattus norvegicus | |||
11. | ALA4452474 | 5b | Activity | = | 23.6 | /min | ALA4326386 | /min | Rattus norvegicus | |||
12. | ALA4452474 | 5b | Activity | = | 24 | /min | ALA4326385 | /min | Rattus norvegicus | |||
13. | ALA4452474 | 5b | Activity | = | 0 | /min | ALA4326384 | /min | Rattus norvegicus | |||
14. | ALA4452474 | 5b | Activity | = | 0.5 | /min | ALA4326383 | /min | Rattus norvegicus | |||
15. | ALA4452474 | 5b | Activity | = | 1.1 | /min | ALA4326382 | /min | Rattus norvegicus | |||
16. | ALA4452474 | 5b | Activity | 0 | ALA4326381 | Non-Toxic | Rattus norvegicus | |||||
17. | ALA4452474 | 5b | Activity | = | 0.2 | g/Kg | ALA4326380 | g/Kg | Rattus norvegicus | |||
18. | ALA4452474 | 5b | Activity | = | 0.49 | g/Kg | ALA4326379 | g/Kg | Rattus norvegicus | |||
19. | ALA4452474 | 5b | Activity | = | 0.81 | g/Kg | ALA4326378 | g/Kg | Rattus norvegicus | |||
20. | ALA4452474 | 5b | BPR | = | 0.5 | ALA4326377 |