| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4454027 | 9 | Stability | = | 99 | % | ALA4350023 | % | ||||
| 2. | ALA4454027 | 9 | Stability | = | 76 | % | ALA4350022 | % | ||||
| 3. | ALA4454027 | 9 | Stability | = | 99 | % | ALA4350021 | % | ||||
| 4. | ALA4454027 | 9 | solubility | = | 19 | uM | ALA4349929 | nM | ||||
| 5. | ALA4454027 | 9 | solubility | < | 1 | uM | ALA4349928 | nM | ||||
| 6. | ALA4454027 | 9 | solubility | < | 1 | uM | ALA4349927 | nM | ||||
| 7. | ALA4454027 | 9 | IC50 | = | 15.5 | uM | ALA4349926 | 4.81 | nM | Homo sapiens | ||
| 8. | ALA4454027 | 9 | IC50 | > | 100 | uM | ALA4349925 | nM | Homo sapiens | |||
| 9. | ALA4454027 | 9 | IC50 | > | 100 | uM | ALA4349924 | nM | Homo sapiens | |||
| 10. | ALA4454027 | 9 | IC50 | = | 67.6 | uM | ALA4349923 | 4.17 | nM | Homo sapiens | ||
| 11. | ALA4454027 | 9 | IC50 | = | 3.8 | uM | ALA4349922 | 5.42 | nM | Homo sapiens | ||
| 12. | ALA4454027 | 9 | IC50 | = | 29.9 | uM | ALA4349921 | 4.52 | nM | Homo sapiens | ||
| 13. | ALA4454027 | 9 | F | = | 53 | % | ALA4349920 | % | ||||
| 14. | ALA4454027 | 9 | t1/2 | = | 4.6 | hr | ALA4349919 | hr | ||||
| 15. | ALA4454027 | 9 | CL | = | 17 | ml/min.kg | ALA4349918 | mL.min-1.kg-1 | ||||
| 16. | ALA4454027 | 9 | AUCt | = | 12.5 | uM.hr | ALA4349917 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 17. | ALA4454027 | 9 | Drug metabolism | < | 0.04 | nmol/min/mg | ALA4349916 | nmol/min/mg | ||||
| 18. | ALA4454027 | 9 | Drug metabolism | = | 0.08 | nmol/min/mg | ALA4349915 | nmol/min/mg | ||||
| 19. | ALA4454027 | 9 | Drug metabolism | < | 0.04 | nmol/min/mg | ALA4349914 | nmol/min/mg | ||||
| 20. | ALA4454027 | 9 | IC50 | = | 28 | nM | ALA4349913 | 7.55 | nM | Homo sapiens |
The page will load shortly, Thanks for your patience!