# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4454542 | 12a; EML741 | Stability | 0 | ALA4401518 | Stable | % | |||||
2. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401534 | Not Active | % | Homo sapiens | ||||
3. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401533 | Not Active | % | Homo sapiens | ||||
4. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401528 | Dose-dependent effect | % | Homo sapiens | ||||
5. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401528 | Tde | % | Homo sapiens | ||||
6. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401527 | Dose-dependent effect | % | Homo sapiens | ||||
7. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401527 | Tde | % | Homo sapiens | ||||
8. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401526 | Dose-dependent effect | % | Homo sapiens | ||||
9. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401526 | Tde | % | Homo sapiens | ||||
10. | ALA4454542 | 12a; EML741 | Activity | 0 | ALA4401525 | Toxic | Homo sapiens | |||||
11. | ALA4454542 | 12a; EML741 | Activity | 0 | ALA4401524 | Non-Toxic | Homo sapiens | |||||
12. | ALA4454542 | 12a; EML741 | Activity | 0 | ALA4401523 | Non-Toxic | ||||||
13. | ALA4454542 | 12a; EML741 | Activity | 0 | ALA4401522 | Non-Toxic | Homo sapiens | |||||
14. | ALA4454542 | 12a; EML741 | Papp | = | 2.3 | 10'-7 cm/s | ALA4401521 | 10'-7 cm/s | ||||
15. | ALA4454542 | 12a; EML741 | Papp | = | 4.8 | 10'-7 cm/s | ALA4401520 | 10'-7 cm/s | ||||
16. | ALA4454542 | 12a; EML741 | Drug metabolism | = | 2.25 | % | ALA4401519 | % | ||||
17. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401517 | Not Active | % | Homo sapiens | ||||
18. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401516 | Not Active | % | Homo sapiens | ||||
19. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401515 | Not Active | % | Homo sapiens | ||||
20. | ALA4454542 | 12a; EML741 | INH | 0 | ALA4401514 | Not Active | % | Homo sapiens |