| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4454999 | 10f | INH | 0 | ALA4387443 | Dose-dependent effect | % | Homo sapiens | ||||
| 2. | ALA4454999 | 10f | Activity | 0 | ALA4387453 | Active | Rattus norvegicus | |||||
| 3. | ALA4454999 | 10f | Activity | 0 | ALA4387460 | Active | Rattus norvegicus | |||||
| 4. | ALA4454999 | 10f | Activity | 0 | ALA4387437 | Dose-dependent effect | Homo sapiens | |||||
| 5. | ALA4454999 | 10f | Activity | 0 | ALA4387458 | Active | Rattus norvegicus | |||||
| 6. | ALA4454999 | 10f | Activity | 0 | ALA4387456 | Active | Rattus norvegicus | |||||
| 7. | ALA4454999 | 10f | Activity | 0 | ALA4387454 | Active | Rattus norvegicus | |||||
| 8. | ALA4454999 | 10f | PPB | = | 99 | % | ALA4387449 | % | ||||
| 9. | ALA4454999 | 10f | PPB | = | 99.7 | % | ALA4387448 | % | ||||
| 10. | ALA4454999 | 10f | Stability | = | 87 | % | ALA4387451 | % | ||||
| 11. | ALA4454999 | 10f | Stability | = | 91 | % | ALA4387450 | % | ||||
| 12. | ALA4454999 | 10f | Papp | = | 51.8 | 10'-6 cm/s | ALA4387447 | 10'-6 cm/s | ||||
| 13. | ALA4454999 | 10f | solubility | > | 95 | uM | ALA4387446 | nM | ||||
| 14. | ALA4454999 | 10f | Activity | 0 | ALA4387445 | Non-Toxic | ||||||
| 15. | ALA4454999 | 10f | Activity | 0 | ALA4387444 | Dose-dependent effect | Homo sapiens | |||||
| 16. | ALA4454999 | 10f | IC50 | = | 4.48 | uM | ALA4387443 | 5.35 | nM | Homo sapiens | ||
| 17. | ALA4454999 | 10f | Ratio EC50 | = | 20 | ALA4387442 | ||||||
| 18. | ALA4454999 | 10f | Ratio EC50 | = | 20 | ALA4387441 | ||||||
| 19. | ALA4454999 | 10f | EC50 | = | 15.93 | uM | ALA4387440 | 4.80 | nM | Rattus norvegicus | ||
| 20. | ALA4454999 | 10f | EC50 | = | 11.27 | uM | ALA4387439 | 4.95 | nM | Mus musculus |
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