Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4455600	(S)-33	CLH	<	1	uL/min	ALA4423297			uL/min
2.	ALA4455600	(S)-33	Papp	=	4.2	10'-6 cm/s	ALA4423296			10'-6 cm/s
3.	ALA4455600	(S)-33	pIC50	=	6.2		ALA4423293	6.20		nM	Homo sapiens
4.	ALA4455600	(S)-33	Activity		0		ALA4423335		Dose-dependent effect		Rattus norvegicus
5.	ALA4455600	(S)-33	Activity		0		ALA4423334		Dose-dependent effect		Rattus norvegicus
6.	ALA4455600	(S)-33	Activity		0		ALA4423333		Dose-dependent effect		Rattus norvegicus
7.	ALA4455600	(S)-33	Activity		0		ALA4423331		Active		Rattus norvegicus
8.	ALA4455600	(S)-33	Activity		0		ALA4423326		Not Active		Rattus norvegicus
9.	ALA4455600	(S)-33	Activity		0		ALA4423325		Not Active		Rattus norvegicus
10.	ALA4455600	(S)-33	F	=	50	%	ALA4423322			%
11.	ALA4455600	(S)-33	beta t1/2	=	0.41	hr	ALA4423315			hr
12.	ALA4455600	(S)-33	CL	=	47	ml/min.Kg	ALA4423312			mL.min-1.kg-1
13.	ALA4455600	(S)-33	Vdss	=	1.2	L/Kg	ALA4423309			L.kg-1
14.	ALA4455600	(S)-33	CLH	=	4.9	uL/min	ALA4423308			uL/min
15.	ALA4455600	(S)-33	Fu	=	60	%	ALA4423307
16.	ALA4455600	(S)-33	Activity		0		ALA4423305		Non-Toxic		Rattus norvegicus
17.	ALA4455600	(S)-33	Activity	=	93	%	ALA4423304			%	Homo sapiens
18.	ALA4455600	(S)-33	pEC50	=	7.9		ALA4423287	7.90		nM	Homo sapiens
19.	ALA4455600	(S)-33	pIC50	<	5		ALA4423302			nM	Homo sapiens
20.	ALA4455600	(S)-33	INH	=	103	%	ALA4423301			%	Rattus norvegicus