# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4457006 | 34 | t1/2 | = | 0.9 | hr | ALA5126282 | hr | ||||
2. | ALA4457006 | 34 | Cmax | = | 10 | ng/ml | ALA5126281 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
3. | ALA4457006 | 34 | AUCt | = | 38.8 | hr.ng/ml | ALA5126280 | ng.hr.mL-1 | ||||
4. | ALA4457006 | 34 | F | = | 2.4 | % | ALA5126278 | % | ||||
5. | ALA4457006 | 34 | CL | = | 51 | ml/min.kg | ALA5126277 | mL.min-1.kg-1 | ||||
6. | ALA4457006 | 34 | t1/2 | = | 1.2 | hr | ALA5126276 | hr | ||||
7. | ALA4457006 | 34 | AUCt | = | 984 | hr.ng/ml | ALA5126275 | ng.hr.mL-1 | ||||
8. | ALA4457006 | 34 | Activity | > | 100 | % | ALA5126261 | % | ||||
9. | ALA4457006 | 34 | Activity | = | 32 | % | ALA5126259 | % | ||||
10. | ALA4457006 | 34 | INH | 0 | ALA4397833 | Dose-dependent effect | % | Mus musculus | ||||
11. | ALA4457006 | 34 | INH | 0 | ALA4397832 | Dose-dependent effect | % | Mus musculus | ||||
12. | ALA4457006 | 34 | INH | 0 | ALA4397831 | Active | % | Mus musculus | ||||
13. | ALA4457006 | 34 | INH | 0 | ALA4397818 | Active | % | Mus musculus | ||||
14. | ALA4457006 | 34 | INH | 0 | ALA4397830 | Active | % | Mus musculus | ||||
15. | ALA4457006 | 34 | INH | 0 | ALA4397828 | Active | % | Mus musculus | ||||
16. | ALA4457006 | 34 | Kd | = | 93.6 | uM | ALA4397827 | 4.03 | nM | Homo sapiens | ||
17. | ALA4457006 | 34 | INH | 0 | ALA4397826 | Dose-dependent effect | % | Mus musculus | ||||
18. | ALA4457006 | 34 | INH | 0 | ALA4397825 | Dose-dependent effect | % | Mus musculus | ||||
19. | ALA4457006 | 34 | INH | = | 100 | % | ALA4397824 | % | Mus musculus | |||
20. | ALA4457006 | 34 | Activity | = | 109.8 | % | ALA4397823 | % |