# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4457647 | 18 | pIC50 | = | 7.4 | ALA4372253 | 7.40 | nM | Homo sapiens | |||
2. | ALA4457647 | 18 | logD | = | 4.1 | ALA4372254 | ||||||
3. | ALA4457647 | 18 | Kinetic_solubility | = | 68 | uM | ALA4372255 | nM | ||||
4. | ALA4457647 | 18 | CLH | = | 2.1 | ml/min/g | ALA4372256 | mL.min-1.g-1 | ||||
5. | ALA4457647 | 18 | Ratio | = | 1.3 | ALA4372257 | Canis lupus familiaris | |||||
6. | ALA4457647 | 18 | permeability | = | 500 | nm/s | ALA4372258 | nm/s | ||||
7. | ALA4457647 | 18 | pIC50 | = | 7 | ALA4372261 | 7.00 | nM | Homo sapiens | |||
8. | ALA4457647 | 18 | pIC50 | = | 6.8 | ALA4372262 | 6.80 | nM | Homo sapiens | |||
9. | ALA4457647 | 18 | INH | = | 84 | % | ALA4372263 | % | Homo sapiens | |||
10. | ALA4457647 | 18 | Fu | = | 13 | % | ALA4372265 | |||||
11. | ALA4457647 | 18 | Fu | = | 4.6 | % | ALA4372266 | |||||
12. | ALA4457647 | 18 | Fu | = | 12.5 | % | ALA4372267 | Homo sapiens | ||||
13. | ALA4457647 | 18 | pIC50 | = | 5.2 | ALA4372268 | 5.20 | nM | Homo sapiens | |||
14. | ALA4457647 | 18 | pEC50 | < | 4.3 | ALA4372269 | nM | Homo sapiens | ||||
15. | ALA4457647 | 18 | pIC50 | = | 4.8 | ALA4372270 | 4.80 | nM | Homo sapiens | |||
16. | ALA4457647 | 18 | pIC50 | < | 4.2 | ALA4372271 | nM | Homo sapiens | ||||
17. | ALA4457647 | 18 | INH | = | 50 | % | ALA4372272 | % | Rattus norvegicus | |||
18. | ALA4457647 | 18 | INH | = | 60 | % | ALA4372273 | % | Rattus norvegicus | |||
19. | ALA4457647 | 18 | INH | = | 70 | % | ALA4372274 | % | Rattus norvegicus | |||
20. | ALA4457647 | 18 | Drug uptake | = | 1126 | ng/ml | ALA4372275 | ng/ml |