# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4458472 | 25 | Activity | 0 | ALA4362390 | Non-Toxic | Homo sapiens | |||||
2. | ALA4458472 | 25 | Activity | 0 | ALA4362385 | Non-Toxic | Homo sapiens | |||||
3. | ALA4458472 | 25 | Activity | 0 | ALA4362381 | Active | Mus musculus | |||||
4. | ALA4458472 | 25 | Activity | 0 | ALA4362387 | Non-Toxic | Homo sapiens | |||||
5. | ALA4458472 | 25 | Activity | 0 | ALA4362377 | Non-Toxic | ||||||
6. | ALA4458472 | 25 | Activity | 0 | ALA4362376 | Non-Toxic | ||||||
7. | ALA4458472 | 25 | Activity | = | 10.5 | % | ALA4362357 | % | Homo sapiens | |||
8. | ALA4458472 | 25 | EC50 | = | 35.4 | nM | ALA4362358 | 7.45 | nM | Homo sapiens | ||
9. | ALA4458472 | 25 | IC50 | = | 3.4 | nM | ALA4362359 | 8.47 | nM | Mus musculus | ||
10. | ALA4458472 | 25 | permeability | = | 10.6 | % | ALA4362360 | % | ||||
11. | ALA4458472 | 25 | t1/2 | = | 3.51 | hr | ALA4362361 | hr | ||||
12. | ALA4458472 | 25 | AUC | = | 1616 | ug.hr/L | ALA4362362 | ng.hr.mL-1 | ||||
13. | ALA4458472 | 25 | CL | = | 103.1 | ml/min.kg | ALA4362363 | mL.min-1.kg-1 | ||||
14. | ALA4458472 | 25 | Vd | = | 31.3 | L/Kg | ALA4362364 | L.kg-1 | ||||
15. | ALA4458472 | 25 | Kinetic_solubility | = | 200 | uM | ALA4362365 | nM | ||||
16. | ALA4458472 | 25 | Activity | 0 | ALA4362375 | Non-Toxic | ||||||
17. | ALA4458472 | 25 | Activity | 0 | ALA4362373 | Non-Toxic | ||||||
18. | ALA4458472 | 25 | Activity | 0 | ALA4362371 | Non-Toxic | Homo sapiens | |||||
19. | ALA4458472 | 25 | Stability | = | 70 | % | ALA4362368 | % | ||||
20. | ALA4458472 | 25 | Stability | = | 94 | % | ALA4362367 | % |