# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | JR14a | 14a; JR14a | EC50 | > | 100 | uM | ALA4380983 | nM | Homo sapiens | |||
2. | JR14a | 14a; JR14a | pIC50 | = | 8 | ALA4380985 | 8.00 | nM | Homo sapiens | |||
3. | JR14a | 14a; JR14a | Activity | 0 | ALA4381018 | Active | Rattus norvegicus | |||||
4. | JR14a | 14a; JR14a | Activity | 0 | ALA4381017 | Active | Rattus norvegicus | |||||
5. | JR14a | 14a; JR14a | Activity | 0 | ALA4381016 | Active | Rattus norvegicus | |||||
6. | JR14a | 14a; JR14a | Activity | 0 | ALA4381015 | Active | Rattus norvegicus | |||||
7. | JR14a | 14a; JR14a | Activity | 0 | ALA4381014 | Active | Rattus norvegicus | |||||
8. | JR14a | 14a; JR14a | Activity | 0 | ALA4381013 | Active | Rattus norvegicus | |||||
9. | JR14a | 14a; JR14a | Activity | 0 | ALA4381012 | Active | Rattus norvegicus | |||||
10. | JR14a | 14a; JR14a | Activity | 0 | ALA4381011 | Active | Rattus norvegicus | |||||
11. | JR14a | 14a; JR14a | Activity | 0 | ALA4381010 | Active | Rattus norvegicus | |||||
12. | JR14a | 14a; JR14a | Activity | 0 | ALA4381009 | Active | Rattus norvegicus | |||||
13. | JR14a | 14a; JR14a | Activity | 0 | ALA4381008 | Active | Rattus norvegicus | |||||
14. | JR14a | 14a; JR14a | Activity | 0 | ALA4381007 | Not Active | Rattus norvegicus | |||||
15. | JR14a | 14a; JR14a | Activity | = | 85 | % | ALA4381006 | % | Rattus norvegicus | |||
16. | JR14a | 14a; JR14a | Activity | = | 65 | % | ALA4381003 | % | Rattus norvegicus | |||
17. | JR14a | 14a; JR14a | CL | = | 4.4 | ml/min.Kg | ALA4381002 | mL.min-1.kg-1 | ||||
18. | JR14a | 14a; JR14a | beta t1/2 | = | 191 | min | ALA4381001 | hr | ||||
19. | JR14a | 14a; JR14a | Vd | = | 0.1 | l | ALA4381000 | l | ||||
20. | JR14a | 14a; JR14a | AUC | = | 3795 | ng.hr/ml | ALA4380999 | ng.hr.mL-1 |