# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA343968 | 25 | IC50 | > | 10000 | nM | ALA805018 | nM | Rattus norvegicus | |||
2. | ALA343968 | 25 | IC50 | = | 33 | nM | ALA795933 | 7.48 | nM | Homo sapiens | ||
3. | ALA343968 | 25 | IC50 | = | 0.76 | nM | ALA801750 | 9.12 | nM | Homo sapiens | ||
4. | ALA343968 | 25 | Bioavailabiility | = | 27 | % | ALA625443 | % | Rattus norvegicus | |||
5. | ALA343968 | 25 | Activity | = | 980 | ng ml-1 | ALA628483 | ng ml-1 | Rattus norvegicus | |||
6. | ALA343968 | 25 | AUC | = | 1300 | ng hr ml-1 | ALA624741 | ng.hr.mL-1 | Rattus norvegicus | |||
7. | ALA343968 | 25 | Bioavailabiility | = | 68 | % | ALA882961 | % | Mustela putorius furo | |||
8. | ALA343968 | 25 | Activity | = | 510 | ng ml-1 | ALA628479 | ng ml-1 | Mustela putorius furo | |||
9. | ALA343968 | 25 | AUC | = | 1100 | ng hr ml-1 | ALA624552 | ng.hr.mL-1 | Mustela putorius furo | |||
10. | ALA343968 | 25 | Bioavailabiility | = | 3.1 | % | ALA625440 | % | ||||
11. | ALA343968 | 25 | Activity | = | 70 | ng ml-1 | ALA628481 | ng ml-1 | ||||
12. | ALA343968 | 25 | AUC | = | 260 | ng hr ml-1 | ALA624554 | ng.hr.mL-1 | ||||
13. | ALA343968 | 25 | Activity | = | 1200 | ng ml-1 | ALA628477 | ng ml-1 | ||||
14. | ALA343968 | 25 | AUC | = | 3400 | ng hr ml-1 | ALA623852 | ng.hr.mL-1 | ||||
15. | ALA343968 | 25 | Change | = | 28 | % | ALA626615 | % | ||||
16. | ALA343968 | 25 | Solubility | = | 0.013 | mg ml-1 | ALA632909 | ug.mL-1 | ||||
17. | ALA343968 | 25 | logD | = | 4.22 | ALA640879 | ||||||
18. | ALA343968 | 25 | IC50 | = | 2.6 | nM | ALA801711 | 8.59 | nM | Homo sapiens | ||
19. | ALA343968 | 25 | Plasma level | = | 560 | ng ml-1 | ALA630829 | ng ml-1 | Rattus norvegicus | |||
20. | ALA343968 | 25 | Plasma level | = | 230 | ng ml-1 | ALA635582 | ng ml-1 | Rattus norvegicus |