# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4460946 | 28 | F | = | 79 | % | ALA4338965 | % | ||||
2. | ALA4460946 | 28 | AUC | = | 676 | ng.hr/ml | ALA4338964 | ng.hr.mL-1 | ||||
3. | ALA4460946 | 28 | t1/2 | = | 12.8 | hr | ALA4338963 | hr | ||||
4. | ALA4460946 | 28 | Vd | = | 18.9 | L/Kg | ALA4338962 | L.kg-1 | ||||
5. | ALA4460946 | 28 | CL | = | 20 | ml/min.kg | ALA4338961 | mL.min-1.kg-1 | ||||
6. | ALA4460946 | 28 | IC50 | = | 67 | nM | ALA4338956 | 7.17 | nM | Homo sapiens | ||
7. | ALA4460946 | 28 | Ki | = | 6 | nM | ALA4338954 | 8.22 | nM | Homo sapiens | ||
8. | ALA4460946 | 28 | permeability | = | 140 | nm/s | ALA4338953 | nm/s | ||||
9. | ALA4460946 | 28 | solubility | = | 9 | uM | ALA4338952 | nM | ||||
10. | ALA4460946 | 28 | EC50 | = | 39 | nM | ALA4338951 | 7.41 | nM | Homo sapiens | ||
11. | ALA4460946 | 28 | IC50 | = | 3.2 | nM | ALA4338950 | 8.49 | nM | Homo sapiens |